Mediator of Cell Motility 1 (MEMO1) (Middle Region) Peptide
MEMO1
适用: 人, 小鼠
宿主: 合成
BP, WB
产品编号 ABIN979984
发货至:
中国
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Contact Info
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中国
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北京 101111
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Quick Overview for Mediator of Cell Motility 1 (MEMO1) (Middle Region) Peptide (ABIN979984)
抗原
MEMO1
(Mediator of Cell Motility 1 (MEMO1))
宿主
人, 小鼠
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- Middle Region
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序列
- CHWGQRFRYS YYDESQGEIY RSIEHLDKMG MSIIEQLDPV SFSNYLKKYH
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产品特性
- This is a synthetic peptide designed for use in combination with anti-Memo1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- MEMO1 (Mediator of Cell Motility 1 (MEMO1))
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背景
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Memo1 may control cell migration by relaying extracellular chemotactic signals to the microtubule cytoskeleton. It is a mediator of ERBB2 signaling. The MEMO1-RHOA-DIAPH1 signaling pathway plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex. It controls the localization of APC and CLASP2 to the cell membrane, via the regulation of GSK3B activity. In turn, membrane-bound APC allows the localization of the MACF1 to the cell membrane, which is required for microtubule capture and stabilization.
Alias Symbols: 0610016J10Rik, D930048L02Rik
Protein Size: 297 -
分子量
- 34 kDa
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基因ID
- 76890
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NCBI登录号
- NM_133771, NP_598532
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UniProt
- Q91VH6
抗原
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