Lysine (K)-Specific Demethylase 4B (KDM4B) (Middle Region) Peptide
KDM4B
适用: 人
宿主: 合成
BP, WB
Quick Overview for Lysine (K)-Specific Demethylase 4B (KDM4B) (Middle Region) Peptide (ABIN978699)
抗原
KDM4B
(Lysine (K)-Specific Demethylase 4B (KDM4B))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- Middle Region
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产品特性
- This is a synthetic peptide designed for use in combination with anti-JMJD2B antibody (Catalog #: ARP58398_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- KDM4B (Lysine (K)-Specific Demethylase 4B (KDM4B))
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背景
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JMJD2 family proteins are classified into one group with JD2H and TUDOR domains and another group without JD2H or TUDOR domains. Because JMJD2C gene (also known as GASC1 gene) is amplified in esophageal squamous cell carcinoma (ESCC), JMJD2 family genes are cancer-associated genes. Human genes corresponding to KIAA0677, KIAA0876, KIAA0780 and FLJ10251 cDNAs were designated JMJD2A, JMJD2B, JMJD2C, and JMJD2D, respectively. In addition, JMJD2D homologous genes within human genome sequences AP002383.3 and AP001264.4 were designated JMJD2E and JMJD2F, respectively. C2HC2HC2- and C5HC2-type Cys (His) clusters were identified as the region conserved among JMJD2A (1064 aa), JMJD2B (1096 aa), and JMJD2C (1056 aa) proteins. JMJD2A, JMJD2B and JMJD2C consist of JmjN, JmjC, JD2H, and two TUDOR domains.
Alias Symbols: FLJ44906, KDM4B, KIAA0876, JMJD2B
Protein Interaction Partner: MED10
Protein Size: 1096 -
分子量
- 122 kDa
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基因ID
- 23030
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NCBI登录号
- NM_015015, NP_055830
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UniProt
- O94953
抗原
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