General Transcription Factor II I Repeat Domain-Containing 1 (GTF2IRD1) Peptide
GTF2IRD1
适用: 人
宿主: 合成
BP, IHC, WB
Quick Overview for General Transcription Factor II I Repeat Domain-Containing 1 (GTF2IRD1) Peptide (ABIN977776)
抗原
GTF2IRD1
(General Transcription Factor II I Repeat Domain-Containing 1 (GTF2IRD1))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
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产品特性
- This is a synthetic peptide designed for use in combination with anti-GTF2IRD1 antibody (Catalog #: ARP33735_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- GTF2IRD1 (General Transcription Factor II I Repeat Domain-Containing 1 (GTF2IRD1))
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背景
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GTF2IRD1 contains five GTF2I-like repeats and each repeat possesses a potential helix-loop-helix (HLH) motif. It may have the ability to interact with other HLH-proteins and function as a transcription factor or as a positive transcriptional regulator under the control of Retinoblastoma protein. GTF2IRD1 is related to Williams-Beuren syndrome, a multisystem developmental disorder. Western blots using three different antibodies against three unique regions of this protein target confirm the same apparent molecular weight in our tests. The protein encoded by this gene contains five GTF2I-like repeats and each repeat possesses a potential helix-loop-helix (HLH) motif. It may have the ability to interact with other HLH-proteins and function as a transcription factor or as a positive transcriptional regulator under the control of Retinoblastoma protein. This gene is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by deletion of multiple genes at 7q11.23. Alternative splicing of this gene generates at least 2 transcript variants.
Alias Symbols: CREAM1, GTF3, MUSTRD1, RBAP2, WBSCR11, WBSCR12, hMusTRD1alpha1, BEN, WBS
Protein Interaction Partner: CDK20,EXOSC4,HDAC3,PIAS2,SMAD3,EXOSC4,HDAC3,HDAC3,NFI1,PIAS2,PIAS2,Pias2
Protein Size: 959 -
分子量
- 106 kDa
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基因ID
- 9569
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NCBI登录号
- NM_016328, NP_057412
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UniProt
- Q9UHL9
抗原
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