GTP Cyclohydrolase 1 (GCH1) (C-Term) Peptide
GCH1
适用: 人
宿主: 合成
BP, WB
Quick Overview for GTP Cyclohydrolase 1 (GCH1) (C-Term) Peptide (ABIN977328)
抗原
GCH1
(GTP Cyclohydrolase 1 (GCH1))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
-
-
蛋白结构域
- C-Term
-
序列
- LRPAGVGVVV EATHMCMVMR GVQKMNSKTV TSTMLGVFRE DPKTREEFLT
-
产品特性
- This is a synthetic peptide designed for use in combination with anti-GCH1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
-
纯化方法
- Purified
-
-
GTP Cyclohydrolase 1 (GCH1) peptide
GCH1 适用: 人, 小鼠, 大鼠 宿主: 合成 BP, Imm
-
-
应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
浓度
- 1 mg/mL
-
缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
-
注意事项
- Avoid repeated freeze-thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
-
- GCH1 (GTP Cyclohydrolase 1 (GCH1))
-
背景
-
This gene encodes a member of the GTP cyclohydrolase family. The encoded protein is the first and rate-limiting enzyme in tetrahydrobiopterin (BH4) biosynthesis, catalyzing the conversion of GTP into 7,8-dihydroneopterin triphosphate. BH4 is an essential cofactor required by aromatic amino acid hydroxylases as well as nitric oxide synthases. Mutations in this gene are associated with malignant hyperphenylalaninemia and dopa-responsive dystonia. Several alternatively spliced transcript variants encoding different isoforms have been described, however, not all variants give rise to a functional enzyme.
Alias Symbols: DYT14, DYT5, DYT5a, GCH, GTP-CH-1, GTPCH1, HPABH4B
Protein Interaction Partner: AHSA1,ATP1B1,GCH1,GCHFR,HSPA8,RAB26,RLF,RPH3A,OSBPL9,RPH3A
Protein Size: 250 -
分子量
- 28 kDa
-
基因ID
- 2643
-
NCBI登录号
- NM_000161, NP_000152
-
UniProt
- P30793
抗原
-
You are here:
