Coilin (COIL) Peptide
COIL
适用: 人
宿主: 合成
BP, WB
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- 抗原 See all Coilin (COIL) products
- Coilin (COIL)
- 宿主
- 人
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB)
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-COIL antibody (Catalog #: ARP53621_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- 纯化方法
- Purified
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- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 浓度
- 1 mg/mL
- 缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- Coilin (COIL)
- 背景
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COIL is an integral component of Cajal bodies (also called coiled bodies). Cajal bodies are nuclear suborganelles of varying number and composition that are involved in the post-transcriptional modification of small nuclear and small nucleolar RNAs. The N-terminus of the coilin protein directs its self-oligomerization while the C-terminus influences the number of nuclear bodies assembled per cell. Differential methylation and phosphorylation of coilin likely influences its localization among nuclear bodies and the composition and assembly of Cajal bodies.The protein encoded by this gene is an integral component of Cajal bodies (also called coiled bodies). Cajal bodies are nuclear suborganelles of varying number and composition that are involved in the post-transcriptional modification of small nuclear and small nucleolar RNAs. The N-terminus of the coilin protein directs its self-oligomerization while the C-terminus influences the number of nuclear bodies assembled per cell. Differential methylation and phosphorylation of coilin likely influences its localization among nuclear bodies and the composition and assembly of Cajal bodies. This gene has pseudogenes on chromosome 4 and chromosome 14. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CLN80, p80-coilin
Protein Interaction Partner: ANKS1B,ANKS1B,ACTN1,ACTN2,ACTN4,ATXN1,BYSL,C1QBP,CCDC136,CCNE1,CDK2,CEP70,CEP76,COIL,CSNK2B,CYB5R2,DHX16,DNAJA3,FAM115A,FHL5,FXR2,GCC1,KALRN,KAZ,KLC2,KLC4,KLHDC5,KLHL8,KPNA3,LNX1,MAD1L1,MYO5B,NIF3L1,NOLC1,NUDT18,PIAS4,PICK1,PLEKHG4,PREPL,PRMT1,PRMT8,PSMA1,PSME3,SART3,SCYL1,SMN2,SNRPB,SNX6,TAF9,TCEB3B,TFCP2,TGS1,TSPYL2,WDYHV1,ZBTB25,ZNF277,ATXN1,CCNE1,COIL,NOLC1,SMN1,SNRPB
Protein Size: 576 - 分子量
- 63 kDa
- 基因ID
- 8161
- NCBI登录号
- NM_004645, NP_004636
- UniProt
- P38432
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