A synthetic peptide for use as a blocking control in assays to test for specificity of IREB2 antibody, Alternative Names: IREB2 control peptide, IREB2 antibody Blocking Peptide, Anti-IREB2 Blocking Peptide, Iron-Responsive Element Binding Protein 2 Blocking Peptide, ACO3 Blocking Peptide, FLJ23381 Blocking Peptide, IRP2 Blocking Peptide, IRP2AD Blocking Peptide, IREB2, IREB-2, IREB 2, IREB-2 Blocking Peptide, IREB 2 Blocking Peptide
Optimal conditions should be determined by the investigator
限制
仅限研究用
状态
Lyophilized
溶解方式
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
缓冲液
PBS
注意事项
Avoid repeated freeze/thaw cycles.
储存条件
-20 °C
储存方法
Store at -20 °C long term.
抗原
IREB2
(Iron-Responsive Element Binding Protein 2 (IREB2))
背景
IREB2 binds to iron-responsive elements (IRES), which are stem-loop structures found in the 5'-UTR of ferritin, and delta aminolevulinic acid synthase mRNAs, and in the 3'-UTR of transferrin receptor mRNA. IREB2 binds to the IRE element in ferritin which results in the repression of its mRNA translation. Binding of the protein to the transferrin receptor mRNA inhibits the degradation of this otherwise rapidly degraded mRNA.