Iron-Responsive Element Binding Protein 2 (IREB2) Peptide
IREB2
适用: 哺乳动物
宿主: 合成
BP, WB, IHC
产品编号 ABIN939499
发货至:
中国
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Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
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Quick Overview for Iron-Responsive Element Binding Protein 2 (IREB2) Peptide (ABIN939499)
抗原
IREB2
(Iron-Responsive Element Binding Protein 2 (IREB2))
宿主
哺乳动物
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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蛋白类型
- Synthetic
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序列
- IQINLNSIVP SVSGPKRPQD RVAVTDMKSD FQACLNEKVG FKGFQIAAEK
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产品特性
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A synthetic peptide for use as a blocking control in assays to test for specificity of IREB2 antibody,
Alternative Names: IREB2 control peptide, IREB2 antibody Blocking Peptide, Anti-IREB2 Blocking Peptide, Iron-Responsive Element Binding Protein 2 Blocking Peptide, ACO3 Blocking Peptide, FLJ23381 Blocking Peptide, IRP2 Blocking Peptide, IRP2AD Blocking Peptide, IREB2, IREB-2, IREB 2, IREB-2 Blocking Peptide, IREB 2 Blocking Peptide
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应用备注
- Optimal conditions should be determined by the investigator
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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缓冲液
- PBS
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C long term.
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- IREB2 (Iron-Responsive Element Binding Protein 2 (IREB2))
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背景
- IREB2 binds to iron-responsive elements (IRES), which are stem-loop structures found in the 5'-UTR of ferritin, and delta aminolevulinic acid synthase mRNAs, and in the 3'-UTR of transferrin receptor mRNA. IREB2 binds to the IRE element in ferritin which results in the repression of its mRNA translation. Binding of the protein to the transferrin receptor mRNA inhibits the degradation of this otherwise rapidly degraded mRNA.
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分子量
- 105 kDa
抗原
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