A synthetic peptide for use as a blocking control in assays to test for specificity of TMEM173 antibody, Alternative Names: TMEM173 control peptide, TMEM173 antibody Blocking Peptide, Anti-TMEM173 Blocking Peptide, Transmembrane Protein 173 Blocking Peptide, FLJ38577 Blocking Peptide, TMEM173, TMEM-173, TMEM 173, TMEM-173 Blocking Peptide, TMEM 173 Blocking Peptide
Optimal conditions should be determined by the investigator
限制
仅限研究用
状态
Lyophilized
溶解方式
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
缓冲液
PBS
注意事项
Avoid repeated freeze/thaw cycles.
储存条件
-20 °C
储存方法
Store at -20 °C long term.
抗原
STING/TMEM173 (TMEM173)
(Transmembrane Protein 173 (TMEM173))
背景
TMEM173 acts as a facilitator of innate immune signaling. It is able to activate both NF-kappa-B and IRF3 transcription pathways to induce expression of type I interferon (IFN-alpha and IFN-beta) and exert a potent anti-viral state following expression. TMEM173 may be involved in translocon function, the translocon possibly being able to influence the induction of type I interferons.It also may be involved in transduction of apoptotic signals via its association with the major histocompatibility complex class II (MHC-II). TMEM173 mediates death signaling via activation of the extracellular signal-regulated kinase (ERK) pathway.