Chemokine (C-C Motif) Receptor 2 (CCR2) (N-Term) Peptide
CCR2
适用: 人
宿主: 合成
BP, WB
Quick Overview for Chemokine (C-C Motif) Receptor 2 (CCR2) (N-Term) Peptide (ABIN2183653)
抗原
CCR2
(Chemokine (C-C Motif) Receptor 2 (CCR2))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- N-Term
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序列
- RSRFIRNTNE SGEEVTTFFD YDYGAPCHKF DVKQIGAQLL PPLYSLVFIF
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产品特性
- This is a synthetic peptide designed for use in combination with anti-CCR2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeat freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- CCR2 (Chemokine (C-C Motif) Receptor 2 (CCR2))
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背景
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This gene encodes two isoforms of a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The receptors encoded by this gene mediate agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This gene is located in the chemokine receptor gene cluster region. Two alternatively spliced transcript variants are expressed by the gene.
Alias Symbols: CC-CKR-2, CCR-2, CCR2A, CCR2B, CD192, CKR2, CKR2A, CKR2B, CMKBR2, MCP-1-R
Protein Size: 360 -
分子量
- 39 kDa
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基因ID
- 729230
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NCBI登录号
- NM_001123396, NP_001116868
抗原
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