(5 references)Quick Overview for SensoLyte® 520 小鼠 Renin Assay Kit (ABIN1882547)
抗原
See all Renin (REN) 试剂盒适用
检测方法
应用范围
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品牌
- SensoLyte®
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产品特性
- The SensoLyte® 520 Mouse Renin Assay Kit provides a convenient assay for high throughput screening of renin inhibitors and for continuous assay of mouse renin activity using a 5-FAM/QXL™520 FRET peptide. In the FRET peptide the fluorescence of 5-FAM is quenched by QXL™520. Upon cleavage into two separate fragments by renin, the fluorescence of 5-FAM is recovered, and can be monitored at excitation/emission = 490/520 nm.
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Renin (REN) ELISA Kit
REN 适用: 人 Colorimetric Sandwich ELISA 31.2 pg/mL - 2000 pg/mL Cell Culture Supernatant, Cell Lysate, Plasma, Serum, Tissue Homogenate
Renin (REN) ELISA KitREN 适用: 大鼠 Colorimetric Sandwich ELISA 15.6 pg/mL - 1000 pg/mL Plasma, Serum
Renin (REN) ELISA KitREN 适用: 小鼠 Colorimetric Sandwich ELISA 0.16 ng/mL - 10 ng/mL Cell Culture Supernatant, Plasma, Serum
Renin (REN) ELISA KitREN 适用: 大鼠 Colorimetric Sandwich ELISA 15.63 pg/mL - 1000 pg/mL Cell Culture Supernatant, Plasma, Serum
Renin (REN) ELISA KitREN 适用: 小鼠 Colorimetric Sandwich ELISA 3.12 pg/mL - 200 pg/mL Plasma, Serum
Renin (REN) ELISA KitREN 适用: 犬 Colorimetric Sandwich ELISA 15.6 pg/mL - 1000 pg/mL Plasma, Serum, Tissue Homogenate
SensoLyte® 520 Renin Assay KitFRET Fluorometric
Renin (REN) ELISA KitREN 适用: 大鼠 Colorimetric Sandwich ELISA 15.625 pg/mL - 1000 pg/mL Plasma, Serum, Tissue Homogenate
Renin (REN) ELISA KitREN 适用: 小鼠 Colorimetric Sandwich ELISA 93.75 pg/mL - 6000 pg/mL Plasma, Serum, Tissue Homogenate
Renin (REN) ELISA KitREN 适用: Pig Colorimetric Sandwich ELISA 78.125 pg/mL - 5000 pg/mL Plasma, Serum, Tissue Homogenate
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说明
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FRET-based Assay Kit
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限制
- 仅限研究用
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储存条件
- -80 °C
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储存方法
- Store all kit components at -20 °C, except for Component C. Store Component C at -80 °C. Protect Components A, B, F, and G from light and moisture. Component D can be stored at room temperature for convenience.
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: "Angiotensin II receptor blocker improves the lowered exercise capacity and impaired mitochondrial function of the skeletal muscle in type 2 diabetic mice." in: Journal of applied physiology (Bethesda, Md. : 1985), Vol. 114, Issue 7, pp. 844-57, (2013) (PubMed).
: "Primary aldosteronism and impaired natriuresis in mice underexpressing TGF?1." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 14, pp. 5600-5, (2013) (PubMed).
: "VDR attenuates acute lung injury by blocking Ang-2-Tie-2 pathway and renin-angiotensin system." in: Molecular endocrinology (Baltimore, Md.), Vol. 27, Issue 12, pp. 2116-25, (2013) (PubMed).
: "Single atom substitution in mouse protein kinase G eliminates oxidant sensing to cause hypertension." in: Nature medicine, Vol. 18, Issue 2, pp. 286-90, (2012) (PubMed).
: "Vitamin D receptor signaling in podocytes protects against diabetic nephropathy." in: Journal of the American Society of Nephrology : JASN, Vol. 23, Issue 12, pp. 1977-86, (2012) (PubMed).
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: "Angiotensin II receptor blocker improves the lowered exercise capacity and impaired mitochondrial function of the skeletal muscle in type 2 diabetic mice." in: Journal of applied physiology (Bethesda, Md. : 1985), Vol. 114, Issue 7, pp. 844-57, (2013) (PubMed).
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- Renin (REN)
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别名
- Renin
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背景
- Renin, a highly specific aspartyl protease, cleaves angiotensinogen, to yield angiotensin I. Angiotensin I is further converted into angiotensin II by ACE (Angiotensin Converting Enzyme). Angiotensin II constricts blood vessels leading to increased blood pressure. Discovery of new renin inhibitors for treatment of hypertension is a promising area of research.
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