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Transferrin Receptor 抗体

Cited in 2+ publications. This 小鼠 单克隆 anti-Transferrin Receptor antibody (Clone B349(DF1513)) specifically detects Transferrin Receptor in FACS 和 IHC (fro). The antibody is reactive with 人 samples.
产品编号 ABIN967201
发货至: 中国
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Quick Overview for Transferrin Receptor 抗体 (ABIN967201)

抗原

See all Transferrin Receptor (TFRC) 抗体
Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

适用

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小鼠

克隆类型

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单克隆

标记

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This Transferrin Receptor antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

克隆位点

B349(DF1513)
  • 特异性

    This antibody reacts with the transferrin receptor, a 180-190 kD transmembrane glycoprotein which exists as a 95 kD homodimer with interchain disulfide bond. The specificity of these antibodies, as demonstrated by immunoprecipitation, are equivalent to OKT9, B3/25 and BerT9.

    纯化方法

    Purified.

    免疫原

    Cell line KG1.

    亚型

    IgG1 kappa
  • 应用备注

    Immunofluorescense 10-20 micrograms/ml.
    Flow cytometry: 1 micrograms/10^6 cells.
    Immunohistochemistry: (Acetone-fixed frozen) 5-15 micrograms/mL using avidin-biotin system. This antibody is an indicator of proliferation activity. It also has prognostic significance when typing tumors, such as leukemias and lymphomas.
    Staining Procedure: This antibody can be used on frozen tissue sections only in IHC.

    说明

    Cellular Localization: Cell membrane.
    Recommended Positive Control: Tonsil

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.4 mg/ml.

    缓冲液

    0.2 mg Immunoglobulin in cell culture supernatant, 50 mM Sodium Borate, 150 mM Sodium Chloride, pH 8.0

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C
  • Friden, Walus, Musso, Taylor, Malfroy, Starzyk: "Anti-transferrin receptor antibody and antibody-drug conjugates cross the blood-brain barrier." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 88, Issue 11, pp. 4771-5, (1991) (PubMed).

    Jing, Spencer, Miller, Hopkins, Trowbridge: "Role of the human transferrin receptor cytoplasmic domain in endocytosis: localization of a specific signal sequence for internalization." in: The Journal of cell biology, Vol. 110, Issue 2, pp. 283-94, (1990) (PubMed).

  • 抗原

    Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

    别名

    Transferrin Receptor,CD71

    分子量

    ~9095 kDa

    基因ID

    7037

    途径

    Transition Metal Ion Homeostasis
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