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Transferrin Receptor 抗体

TFRC 适用: 人 FACS, IHC (fro) 宿主: 小鼠 Monoclonal B349(DF1513) unconjugated
产品编号 ABIN967201
发货至: 中国
  • 抗原 See all Transferrin Receptor (TFRC) 抗体
    Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))
    适用
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    宿主
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    小鼠
    克隆类型
    • 163
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    单克隆
    标记
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    This Transferrin Receptor antibody is un-conjugated
    应用范围
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    Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))
    特异性
    This antibody reacts with the transferrin receptor, a 180-190 kD transmembrane glycoprotein which exists as a 95 kD homodimer with interchain disulfide bond. The specificity of these antibodies, as demonstrated by immunoprecipitation, are equivalent to OKT9, B3/25 and BerT9.
    纯化方法
    Purified.
    免疫原
    Cell line KG1.
    克隆位点
    B349(DF1513)
    亚型
    IgG1 kappa
    Top Product
    Discover our top product TFRC Primary Antibody
  • 应用备注
    Immunofluorescense 10-20 micrograms/ml.
    Flow cytometry: 1 micrograms/10^6 cells.
    Immunohistochemistry: (Acetone-fixed frozen) 5-15 micrograms/mL using avidin-biotin system. This antibody is an indicator of proliferation activity. It also has prognostic significance when typing tumors, such as leukemias and lymphomas.
    Staining Procedure: This antibody can be used on frozen tissue sections only in IHC.
    说明

    Cellular Localization: Cell membrane.
    Recommended Positive Control: Tonsil

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.4 mg/ml.
    缓冲液
    0.2 mg Immunoglobulin in cell culture supernatant, 50 mM Sodium Borate, 150 mM Sodium Chloride, pH 8.0
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
  • Friden, Walus, Musso, Taylor, Malfroy, Starzyk: "Anti-transferrin receptor antibody and antibody-drug conjugates cross the blood-brain barrier." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 88, Issue 11, pp. 4771-5, (1991) (PubMed).

    Jing, Spencer, Miller, Hopkins, Trowbridge: "Role of the human transferrin receptor cytoplasmic domain in endocytosis: localization of a specific signal sequence for internalization." in: The Journal of cell biology, Vol. 110, Issue 2, pp. 283-94, (1990) (PubMed).

  • 抗原
    Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))
    别名
    Transferrin Receptor,CD71 (TFRC 产品)
    分子量
    ~9095 kDa
    基因ID
    7037
    途径
    Transition Metal Ion Homeostasis
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