APOE 抗体
(1 reference)Our Local Distributor
北京 101111
Quick Overview for APOE 抗体 (ABIN965577)
抗原
See all APOE 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
纯化方法
- Ascitic fluid
-
免疫原
- Purified recombinant fragment of human ApoE expressed in E. Coli.
-
亚型
- IgG1
-
-
anti-Apolipoprotein E (APOE) (AA 19-181) antibody
APOE 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Apolipoprotein E (APOE) (AA 19-168) antibodyAPOE 适用: 大鼠 WB, IHC, IP, ICC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Apolipoprotein E (APOE) (AA 1-172) antibodyAPOE 适用: 犬 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Apolipoprotein E (APOE) (AA 19-168) antibodyAPOE 适用: 大鼠 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C5 unconjugated
anti-Apolipoprotein E (APOE) (C-Term) antibodyAPOE 适用: 人 WB, ELISA, IP, ICC, IHC (p), IF, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Apolipoprotein E (APOE) (AA 200-300) antibodyAPOE 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Apolipoprotein E (APOE) antibodyAPOE 适用: 人 IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 1H4 unconjugated
anti-Apolipoprotein E (APOE) (N-Term) antibodyAPOE 适用: 人 WB, ICC, IHC (p), IF 宿主: 兔 Polyclonal unconjugated
anti-Apolipoprotein E (APOE) (AA 151-250) antibodyAPOE 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Apolipoprotein E (APOE) (AA 14-167) antibodyAPOE 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
Western Bloting: 1/500 - 1/2000.
Immunohistochemistry: 1/200 - 1/1000.
Flow cytometry: 1/200 - 1/400.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test. -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C
-
-
-
: "APOE gene polymorphisms and response to statin therapy." in: The pharmacogenomics journal, Vol. 9, Issue 4, pp. 248-57, (2009) (PubMed).
-
: "APOE gene polymorphisms and response to statin therapy." in: The pharmacogenomics journal, Vol. 9, Issue 4, pp. 248-57, (2009) (PubMed).
-
- APOE (Apolipoprotein E (APOE))
-
别名
- ApoE
-
背景
-
Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptormediated endocytosis in the liver. Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells. ApoE is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. The APOE gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants.
Tissue specificity: Occurs in all lipoprotein fractions in plasma. It constitutes 10-20% of very low density lipoproteins (VLDL) and 1-2% of high density lipoproteins (HDL). APOE is produced in most organs. Significant quantities are produced in liver, brain, spleen, lung, adrenal, ovary, kidney and muscle.
Synonyms: AD2, LPG, LDLCQ5, MGC1571 -
分子量
- 36kDa
-
基因ID
- 348
-
途径
- Regulation of Cell Size, Lipid Metabolism
抗原
-
