Complement C2 抗体 (N-Term)
Our Local Distributor
北京 101111
Quick Overview for Complement C2 抗体 (N-Term) (ABIN951633)
抗原
See all Complement C2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 150-180, N-Term
-
特异性
- This antibody reacts to Complement C2.
-
交叉反应 (详细)
- Species reactivity (tested):Human and Hamster.
-
纯化方法
- Affinity chromatography on Protein A
-
免疫原
- KLH conjugated synthetic peptide between 150-180 amino acids from the N-terminal region of human C2
-
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 0.25 mg/mL
-
缓冲液
- PBS containing 0.09 % (W/V) sodium azide as preservative
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
-
-
- Complement C2
-
背景
- Component C2 is a serum glycoprotein that functions as part of the classical pathway of the complement system. Activated C1 cleaves C2 into C2a and C2b. The serine proteinase C2a then combines with complement factor 4b to create the C3 or C5 convertase. Deficiency of C2 has been reported to associated with certain autoimmune diseases and SNPs in this gene have been associated with altered susceptibility to age-related macular degeneration. This gene localizes within the class III region of the MHC on the short arm of chromosome 6. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described in publications but their full-length sequence has not been determined.Synonyms: C2, C3/C5 convertase, Complement component 2
-
基因ID
- 717
-
NCBI登录号
- NP_000054
抗原
-