Factor XI 抗体 (C-Term)
Quick Overview for Factor XI 抗体 (C-Term) (ABIN926655)
抗原
See all Factor XI (F11) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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纯化方法
- Purified
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免疫原
- F11 antibody was raised in rabbit using the C terminal of F11 as the immunogen
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应用备注
- Optimal conditions should be determined by the investigator.
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说明
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F11 Blocking Peptide, (ABIN5613441), is also available for use as a blocking control in assays to test for specificity of this F11 antibody
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限制
- 仅限研究用
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状态
- Lyophilized
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浓度
- Lot specific
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缓冲液
- Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
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- Factor XI (F11) (Coagulation Factor XI (F11))
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别名
- F11
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背景
- This gene encodes coagulation factor XI of the blood coagulation cascade. This protein is present in plasma as a zymogen, which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds. During activation of the plasma factor XI, an internal peptide bond is cleaved by factor XIIa (or XII) in each of the two chains, resulting in activated factor XIa, a serine protease composed of two heavy and two light chains held together by disulfide bonds. This activated plasma factor XI triggers the middle phase of the intrisic pathway of blood coagulation by activating factor IX. Defects in this factor lead to Rosenthal syndrome, a blood coagulation abnormality. Synonyms: Polyclonal F11 antibody, Anti-F11 antibody, coagulation factor XI antibody, FXI antibody, MGC141891 antibody.
抗原
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