APOB 抗体
Our Local Distributor
北京 101111
Quick Overview for APOB 抗体 (ABIN865414)
抗原
See all APOB 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
纯化方法
- Ascitic fluid
-
免疫原
- Purified recombinant fragment of human ApoB expressed in E. Coli.
-
亚型
- IgG1
-
-
-
-
应用备注
- WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000, FC: 1/200 - 1/400 ELISA: Propose dilution 1/10000.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 100g/100l
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C
-
-
- APOB (Apolipoprotein B (APOB))
-
别名
- ApoB
-
背景
- This gene product is the main apolipoprotein of chylomicrons and low density lipoproteins. It occurs in plasma as two main isoforms, apoB-48 and apoB-100: the former is synthesized exclusively in the gut and the latter in the liver. The intestinal and the hepatic forms of apoB are encoded by a single gene from a single, very long mRNA. The two isoforms share a common N-terminal sequence. The shorter apoB-48 protein is produced after RNA editing of the apoB-100 transcript at residue 2180 (CAA->UAA), resulting in the creation of a stop codon, and early translation termination. Mutations in this gene or its regulatory region cause hypobetalipoproteinemia, normotriglyceridemic hypobetalipoproteinemia, and hypercholesterolemia due to ligand-defective apoB, diseases affecting plasma cholesterol and apoB levels. Synonyms: FLDB, LDLCQ4
-
分子量
- 516kDa
-
基因ID
- 338
-
途径
- Lipid Metabolism
抗原
-