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APOB 抗体

This anti-APOB antibody is a 小鼠 单克隆 antibody detecting APOB in WB, IHC, ELISA 和 FACS. Suitable for 人.
产品编号 ABIN865414
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for APOB 抗体 (ABIN865414)

抗原

See all APOB 抗体
APOB (Apolipoprotein B (APOB))

适用

  • 116
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宿主

  • 80
  • 47
  • 14
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小鼠

克隆类型

  • 84
  • 60
单克隆

标记

  • 62
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This APOB antibody is un-conjugated

应用范围

  • 86
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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)

克隆位点

6G6
  • 纯化方法

    Ascitic fluid

    免疫原

    Purified recombinant fragment of human ApoB expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000, FC: 1/200 - 1/400 ELISA: Propose dilution 1/10000.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    100g/100l

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C
  • 抗原

    APOB (Apolipoprotein B (APOB))

    别名

    ApoB

    背景

    This gene product is the main apolipoprotein of chylomicrons and low density lipoproteins. It occurs in plasma as two main isoforms, apoB-48 and apoB-100: the former is synthesized exclusively in the gut and the latter in the liver. The intestinal and the hepatic forms of apoB are encoded by a single gene from a single, very long mRNA. The two isoforms share a common N-terminal sequence. The shorter apoB-48 protein is produced after RNA editing of the apoB-100 transcript at residue 2180 (CAA->UAA), resulting in the creation of a stop codon, and early translation termination. Mutations in this gene or its regulatory region cause hypobetalipoproteinemia, normotriglyceridemic hypobetalipoproteinemia, and hypercholesterolemia due to ligand-defective apoB, diseases affecting plasma cholesterol and apoB levels. Synonyms: FLDB, LDLCQ4

    分子量

    516kDa

    基因ID

    338

    途径

    Lipid Metabolism
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