Apelin 抗体 (AA 24-77)
Quick Overview for Apelin 抗体 (AA 24-77) (ABIN7600858)
抗原
See all Apelin (APLN) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 24-77
-
原理
- Anti-Apelin/APLN Antibody
-
交叉反应 （详细）
- No cross-reactivity with other proteins.
-
产品特性
- Anti-Apelin/APLN Antibody Picoband® (ABIN7600858). Tested in ELISA, IHC applications. This antibody reacts with Human.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived human Apelin/APLN recombinant protein (Position: S24-F77).
-
亚型
- IgG
-
-
anti-Apelin (APLN) (C-Term) antibody
APLN 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Apelin (APLN) (AA 23-77) antibodyAPLN 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Apelin (APLN) (AA 1-122) antibodyAPLN 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2A1-2D5 unconjugated
anti-Apelin (APLN) (AA 1-122) antibodyAPLN 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Apelin (APLN) (C-Term) antibodyAPLN 适用: 人, 小鼠, 猴 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Apelin (APLN) (C-Term) antibodyAPLN 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Apelin (APLN) (AA 1-122) antibodyAPLN 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Apelin (APLN) (AA 1-122) antibodyAPLN 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Apelin (APLN) (AA 24-77) antibodyAPLN 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Cayabyab, M., Hinuma, S., Farzan, M., Choe, H., Fukusumi, S., Kitada, C., Nishizawa, N., Hosoya, M., Nishimura, O., Messele, T., Pollakis, G., Goudsmit, J., Fujino, M., Sodroski, J. Apelin, the natural ligand of the orphan seven-transmembrane receptor APJ, inhibits human immunodeficiency virus type 1 entry.J. Virol. 74: 11972-11976, 2000. 2. Chen, M. M., Ashley, E. A., Deng, D. X. F., Tsalenko, A., Deng, A., Tabibiazar, R., Ben-Dor, A., Fenster, B., Yang, E., King, J. Y., Fowler, M., Robbins, R., Johnson, F. L., Bruhn, L., McDonagh, T., Dargie, H., Yakhini, Z., Tsao, P. S., Quertermous, T.Novel role for the potent endogenous inotrope apelin in human cardiac dysfunction.Circulation 108: 1432-1439, 2003. 3. De Mota, N., Reaux-Le Goazigo, A., El Messari, S., Chartrel, N., Roesch, D., Dujardin, C., Kordon, C., Vaudry, H., Moos, F., Llorens-Cortes, C. Apelin, a potent diuretic neuropeptide counteracting vasopressin actions through inhibition of vasopressin neuron activity and vasopressin release.Proc. Nat. Acad. Sci. 101: 10464-10469, 2004. -
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
-
-
- Apelin (APLN)
-
别名
- APLN
-
背景
-
Synonyms: Deleted in azoospermia-like, DAZ homolog, DAZ-like autosomal, Deleted in azoospermia-like 1, SPGY-like-autosomal, DAZL, DAZH, DAZL1, DAZLA, SPGYLA
Background: Apelin is a neuropeptide expressed in the supraoptic and paraventricular nuclei that acts on specific receptors located on vasopressinergic neurons. The apelin gene to Xq25-q26.3 based on sequence similarity between the apelin sequence and a chromosome X PAC clone. This gene encodes a peptide that functions as an endogenous ligand for the G protein coupled receptor APJ. The encoded protein is synthesized as a prepropeptide that is processed into biologically active C-terminal fragments. The peptide fragments activate different tissue specific signaling pathways that regulate diverse biological functions including fluid homeostasis, cardiovascular function and insulin secretion. This protein also functions as a coreceptor for the human immunodeficiency virus 1.
-
分子量
- 41 kDa
-
基因ID
- 8862
-
途径
- Positive Regulation of Peptide Hormone Secretion, Hormone Activity, Feeding Behaviour
抗原
-
