ENPP2 抗体
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北京 101111
Quick Overview for ENPP2 抗体 (ABIN7581209)
抗原
See all ENPP2 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Goat polycolonal antibody targeting human Autotaxin (ATX)
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特异性
- Anti-ATX antibody recognizes endogenous human ATX and is predicted to recognize rat, mouse, horse, and feline ATX based on amino acid conservation.
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纯化方法
- affinity purified
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免疫原
- ATX peptide
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亚型
- IgG
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应用备注
- WB – 1:1000, ELISA – 1:1000 Other in vitro and cellular applications are possible using this antibody, but have not been verified.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS, pH 7.4
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储存条件
- 4 °C,-20 °C
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储存方法
- Antibody is stable for up to 1 year at -20°C. Antibody is stable at 4°C for up to 60 days. Avoid repeated freeze/thaw cycles.
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- ENPP2 (Ectonucleotide Pyrophosphatase / phosphodiesterase 2 (ENPP2))
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别名
- Autotaxin
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背景
- ATX, also known as ENPP2, cleaves choline from lysophosphatidylcholine forming lysophosphatidic acid (LPA), a potent mitogen that has been implicated in the pathophysiology of ovarian cancer. ATX has been demonstrated to increase cell motility, neovascularization, proliferation, and aggressiveness of tumors and is upregulated in numerous cancer lineages (non-small cell lung , glioma, mammary carcinoma, renal cell carcinoma, hepatocellular carcinoma). In addition, dysregulation of the ATX/LPA pathway is central to the pathophysiology of idiopathic pulmonary fibrosis, rheumatoid arthritis, and other inflammatory diseases.
抗原
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