CCR7 抗体
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北京 101111
Quick Overview for CCR7 抗体 (ABIN7539624)
抗原
See all CCR7 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- AF/LE Purified Anti-Human CD197 Antibody [G043H7]
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特异性
- Human
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纯化方法
- Protein A/G Purified
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内毒素水平
- Low Endotoxin: < 1.0 EU per mg of the antibody as determined by the LAL method.
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免疫原
- Recombinant Human CD197 protein
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亚型
- IgG2a, kappa
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应用备注
- FCM:2 μg/mL(1x10^5-5x10^5 cells)
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- ≥ 1 mg/mL
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缓冲液
- Sterile PBS.
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
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- CCR7 (Chemokine (C-C Motif) Receptor 7 (CCR7))
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别名
- CD197
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背景
- The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. Signals mediated by this receptor regulate T cell homeostasis in lymph nodes, and may also function in the activation and polarization of T cells, and in chronic inflammation pathogenesis. Alternative splicing of this gene results in multiple transcript variants.
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基因ID
- 1236
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UniProt
- P32248
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途径
- Regulation of Actin Filament Polymerization, Positive Regulation of Immune Effector Process
抗原
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