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CCR7 抗体

This anti-CCR7 antibody is a 小鼠 单克隆 antibody detecting CCR7 in FACS. Suitable for 人.
产品编号 ABIN7539624
发货至: 中国

Quick Overview for CCR7 抗体 (ABIN7539624)

抗原

See all CCR7 抗体
CCR7 (Chemokine (C-C Motif) Receptor 7 (CCR7))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CCR7 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS)

克隆位点

G043H7
  • 原理

    AF/LE Purified Anti-Human CD197 Antibody [G043H7]

    特异性

    Human

    纯化方法

    Protein A/G Purified

    内毒素水平

    Low Endotoxin: < 1.0 EU per mg of the antibody as determined by the LAL method.

    免疫原

    Recombinant Human CD197 protein

    亚型

    IgG2a, kappa
  • 应用备注

    FCM:2 μg/mL(1x10^5-5x10^5 cells)

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    ≥ 1 mg/mL

    缓冲液

    Sterile PBS.

    储存液

    Azide free

    储存条件

    4 °C,-20 °C

    储存方法

    Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
  • 抗原

    CCR7 (Chemokine (C-C Motif) Receptor 7 (CCR7))

    别名

    CD197

    背景

    The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. Signals mediated by this receptor regulate T cell homeostasis in lymph nodes, and may also function in the activation and polarization of T cells, and in chronic inflammation pathogenesis. Alternative splicing of this gene results in multiple transcript variants.

    基因ID

    1236

    UniProt

    P32248

    途径

    Regulation of Actin Filament Polymerization, Positive Regulation of Immune Effector Process
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