Kininogen-1 Heavy Chain (AA 300-380), (Cleaved-Lys380) 抗体
This 兔 多克隆 anti-not_set antibody specifically detects not_set in ELISA 和 WB. The antibody is reactive with 人 samples.
产品编号 ABIN7222046
发货至:
中国
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Quick Overview for Kininogen-1 Heavy Chain (AA 300-380), (Cleaved-Lys380) 抗体 (ABIN7222046)
抗原
Kininogen-1 Heavy Chain
适用
人
宿主
兔
克隆类型
多克隆
标记
非结合性
应用范围
ELISA, Western Blotting (WB)
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抗原表位
- AA 300-380, Cleaved-Lys380
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原理
- Cleaved-Kininogen-1 HC (K380) Polyclonal Antibody
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特异性
- Cleaved-Kininogen-1 HC (K380) Polyclonal Antibody detects endogenous levels of fragment of activated Kininogen-1 HC protein resulting from cleavage adjacent to K380.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from the Internal region of human Kininogen-1 HC at AA range: 300-380
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亚型
- IgG
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anti-Kininogen-1 Heavy Chain (Lys380) antibody
适用: 人 ELISA, WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- Kininogen-1 Heavy Chain
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别名
- Kininogen-1 HC
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背景
- Rabbit Anti-Cleaved-Kininogen-1 HC (K380) Polyclonal Antibody,KNG1, BDK, KNG, Kininogen-1, Alpha-2-thiol proteinase inhibitor, Fitzgerald factor, High molecular weight kininogen, HMWK, Williams-Fitzgerald-Flaujeac factor,KNG1 uses alternative splicing to generate two different proteins- high molecular weight kininogen (HMWK) and low molecular weight kininogen (LMWK). HMWK is essential for blood coagulation and assembly of the kallikrein-kinin system. Also, bradykinin, a peptide causing numerous physiological effects, is released from HMWK. Bradykinin also functions as an antimicrobial peptide with antibacterial and antifungal activity. In contrast to HMWK, LMWK is not involved in blood coagulation. Three transcript variants encoding different isoforms have been found for this gene.,Kininogen-1
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分子量
- observerd band 41kDa
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基因ID
- 3827
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UniProt
- P01042
抗原
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