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Ataxin-7L1 (AA 410-490) 抗体

This anti-Ataxin-7L1 antibody is a 兔 多克隆 antibody detecting Ataxin-7L1 in ELISA 和 IHC (p). Suitable for 人 和 小鼠.
产品编号 ABIN7220502
发货至: 中国
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Quick Overview for Ataxin-7L1 (AA 410-490) 抗体 (ABIN7220502)

抗原

Ataxin-7L1

适用

人, 小鼠

宿主

  • 1

克隆类型

  • 1
多克隆

标记

  • 1
非结合性

应用范围

ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    AA 410-490

    原理

    Ataxin-7L1 Polyclonal Antibody

    特异性

    Ataxin-7L1 Polyclonal Antibody detects endogenous levels of Ataxin-7L1 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

    免疫原

    Synthesized peptide derived from the Internal region of human Ataxin-7L1 at AA range: 410-490

    亚型

    IgG
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:300), ELISA (1:10000). Not yet tested in other applications.

    说明

    Primary Antibody

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
  • 抗原

    Ataxin-7L1

    背景

    Rabbit Anti-Ataxin-7L1 Polyclonal Antibody,ATXN7L1, ATXN7L4, KIAA1218, Ataxin-7-like protein 1, Ataxin-7-like protein 4,ATXN7L3 (ataxin-7-like protein 3) is a 347 amino acid transcription protein that belongs to the SGF11 family. ATXN7L3 localizes to nucleus and contains one SCA7 domain and one SGF11-type zinc finger. The SGF11-type zinc finger of ATXN7L3 mediates the interaction with USP22 and ENY2. ATXN7L3 is a component of the transcription regulatory histone acetylation (HAT) complex SAGA, which is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, ATXN7L3 contributes to a subcomplex that specifically deubiquitinates both histones H2A and H2B. The ATXN7L3 gene exists as two alternatively spliced isoforms, is conserved in chimpanzee, dog, cow, rat, zebrafish, fruit fly and mosquito, and maps to human chromosome 17q21.1.,Ataxin-7-like protein 1

    基因ID

    222255

    UniProt

    Q9ULK2
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