14-3-3 Pan (acLys49), (acLys51) 抗体
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北京 101111
Quick Overview for 14-3-3 Pan (acLys49), (acLys51) 抗体 (ABIN7226752)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- acLys49, acLys51
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原理
- 14-3-3-pan (Acetyl Lys51/49) Polyclonal Antibody
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特异性
- Acetyl-14-3-3-pan (K51/49) Polyclonal Antibody detects endogenous levels of 14-3-3-pan around the acetylation site of K51 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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免疫原
- Synthesized peptide derived from human 14-3-3-pan around the acetylation site of K51
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亚型
- IgG
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000). Not yet tested in other applications.
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说明
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Primary Antibody
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- 14-3-3 Pan
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别名
- 14-3-3-pan
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背景
- Rabbit Anti-14-3-3-pan (Acetyl Lys51/49) Polyclonal Antibody,YWHAB (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta) encodes a protein belonging to the 14-3-3 family of proteins, members of which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals. The encoded protein has been shown to interact with RAF1 and CDC25 phosphatases, suggesting that it may play a role in linking mitogenic signaling and the cell cycle machinery. Two transcript variants, which encode the same protein, have been identified for YWHAB.,14-3-3 protein beta
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基因ID
- 7529
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UniProt
- P31946
抗原
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