TMEM123 抗体
Quick Overview for TMEM123 抗体 (ABIN7131392)
抗原
See all TMEM123 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- TMEM123 Antibody
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纯化方法
- Antigen affinity purification
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免疫原
- Fusion protein of Human TMEM123
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C,-80 °C
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储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- TMEM123 (Transmembrane Protein 123 (TMEM123))
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别名
- TMEM123
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背景
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Background: This gene encodes a highly glycosylated transmembrane protein with a high content of threonine and serine residues in its extracellular domain, similar to a broadly defined category of proteins termed mucins. Exposure of some cell types to anti-PORIMIN (pro-oncosis receptor inducing membrane injury) antibody, crosslinks this protein on the cell surface and induces a type of cell death termed oncosis. Oncosis is distinct from apoptosis and is characterized by a loss of cell membrane integrity without DNA fragmentation. This gene product is proposed to function as a cell surface receptor that mediates cell death.
Aliases: TMEM123 antibody, KCT3 antibody, PSEC0111 antibody, UNQ641/PRO1271 antibody, Porimin antibody, Keratinocytes-associated transmembrane protein 3 antibody, KCT-3 antibody, Pro-oncosis receptor inducing membrane injury antibody, Transmembrane protein 123 antibody
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UniProt
- Q8N131
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途径
- Regulation of Cell Size
抗原
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