OB Cadherin 抗体
Our Local Distributor
北京 101111
Quick Overview for OB Cadherin 抗体 (ABIN7073255)
抗原
See all OB Cadherin (CDH11) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
交叉反应
- 人, 大鼠
-
纯化方法
- Affinity purification
-
免疫原
- KLH conjugated Synthetic peptide corresponding to Mouse OB Cadherin
-
-
-
-
应用备注
- WB (H,M,R) 1: 500-1: 1000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS, pH 7.4, 0.02 % sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
-
- OB Cadherin (CDH11) (Cadherin 11 (CDH11))
-
别名
- OB Cadherin
-
背景
- The cadherin super family comprises a large number of membrane glycoproteins with one or more cadherin repeats, which are involved in Ca2+ dependent cell-cell adhesion. Cadherin-11, also known as OB-cadherin, is a type II classical cadherin. Classical cadherins are type I transmembrane proteins with an N-terminal extracellular domain containing five tandem cadherin repeats and a C-terminal cytoplasmic domain with a characteristic sequence for binding to catenins. Type I cadherins differ from type II cadherins by the presence of the HAV tripeptide motif in the most N-terminal cadherin repeat. Classic cadherins mediate cell-cell adhesion preferentially via homotypic interactions and form adherens juctions that have beta -catenin and p120 (ctn) at the cytoplasmic side of the junction. Homotypic cadherin interactions also transduce outside-in and inside-out cell signals.
-
分子量
- 120 kDa
-
基因ID
- 12552
-
NCBI登录号
- NP_033996
-
UniProt
- P55288
抗原
-