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RORC 抗体

This anti-RORC antibody is a 兔 多克隆 antibody detecting RORC in WB 和 ELISA. Suitable for 人 和 小鼠.
产品编号 ABIN7251244
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for RORC 抗体 (ABIN7251244)

抗原

See all RORC 抗体
RORC (RAR-Related Orphan Receptor C (RORC))

适用

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人, 小鼠

宿主

  • 89
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  • 2
  • 1
  • 1

克隆类型

  • 92
  • 19
多克隆

标记

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This RORC antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 产品特性

    Polyclonal Antibody

    纯化方法

    Affinity purification

    免疫原

    Synthesized peptide derived from the Internal region of human RORC

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000, ELISA 1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    RORC (RAR-Related Orphan Receptor C (RORC))

    别名

    RORC

    背景

    The protein encoded by this gene is a DNA-binding transcription factor and is a member of the NR1 subfamily of nuclear hormone receptors. The specific functions of this protein are not known, however, studies of a similar gene in mice have shown that this gene may be essential for lymphoid organogenesis and may play an important regulatory role in thymopoiesis. In addition, studies in mice suggest that the protein encoded by this gene may inhibit the expression of Fas ligand and IL2. Two transcript variants encoding different isoforms have been found for this gene.RORC (RAR Related Orphan Receptor C) is a Protein Coding gene. Diseases associated with RORC include Immunodeficiency 42 and Anus Cancer. Among its related pathways are Circadian rythm related genes and Innate Immune System. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and steroid hormone receptor activity. An important paralog of this gene is RORA.

    分子量

    Observed_MW: 58 kDa

    Calculated_MW: 58 kDa

    UniProt

    P51449

    途径

    Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway
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