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PDGFRB 抗体 (AA 911-992)

PDGFRB 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6654145
发货至: 中国
  • 抗原 See all PDGFRB 抗体
    PDGFRB (Platelet Derived Growth Factor Receptor beta (PDGFRB))
    抗原表位
    • 25
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    AA 911-992
    适用
    • 191
    • 72
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    • 4
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    • 1
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    人, 小鼠, 大鼠
    宿主
    • 168
    • 26
    • 3
    • 2
    克隆类型
    • 159
    • 40
    多克隆
    标记
    • 104
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    This PDGFRB antibody is un-conjugated
    应用范围
    • 148
    • 70
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    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    Antigen affinity purified
    免疫原
    Human PDGFRB recombinant protein (amino acids E911-L992) was used as the immunogen for the PDGFRB antibody.
    亚型
    IgG
    Top Product
    Discover our top product PDGFRB Primary Antibody
  • 应用备注
    Optimal dilution of the PDGFRB antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL,Immunohistochemistry (FFPE): 1-2 μg/mL,Direct ELISA: 0.1-0.5 μg/mL
    限制
    仅限研究用
  • 缓冲液
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    储存条件
    -20 °C
    储存方法
    After reconstitution, the PDGFRB antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原
    PDGFRB (Platelet Derived Growth Factor Receptor beta (PDGFRB))
    别名
    Platelet Derived Growth Factor Receptor beta / PDGFRB (PDGFRB 产品)
    背景
    Beta-type platelet-derived growth factor receptor is a protein that in humans is encoded by the PDGFRB gene. The protein encoded by this gene is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer (PDGFB or PDGFD) or a heterodimer (PDGFA and PDGFB). This gene is essential for normal development of the cardiovascular system and aids in rearrangement of the actin cytoskeleton. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor, all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the ETV6 gene, results in chronic myeloproliferative disorder with eosinophilia.
    UniProt
    P09619
    途径
    Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Inositol Metabolic Process, Glycosaminoglycan Metabolic Process, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling
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