CD47 抗体
Quick Overview for CD47 抗体 (ABIN6296670)
抗原
See all CD47 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Mouse anti-Human CD47 Antibody [Sodium Azide Free]
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特异性
- Cell surface, cytoplasmic
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纯化方法
- Intact CD47 purified from placenta was used as the immunogen for this antibody.
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免疫原
- Intact CD47 purified from placenta was used as the immunogen for this antibody.
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应用备注
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Functional Activity (Blocking): Order BSA/Azide-free format
FACS: 0.5-1 μg/million cells
IF: 1-2 μg/mL
IHC (FFPE): 0.5-1 μg/mL for 30 min at RT
Western blot: 2-5 μg/mL -
限制
- 仅限研究用
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缓冲液
- In 1X PBS ( pH 7.4), BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- CD47
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别名
- Leukocyte surface antigen CD47
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背景
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Target Description: This antibody reacts with the Ig domain of CD47 protein. It has been shown to inhibit polymorphonuclear neutrophil (PMN) transmigration across cell monolayers and matrix. CD47, originally named integrin-associated protein (IAP), is a 50 kDa protein containing five membrane-spanning sequences and a short cytoplasmic tail. CD47 plays a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. It is important in memory formation and synaptic plasticity in the hippocampus. CD47 may play a role in membrane transport and/or integrin dependent signal transduction.
Gene Symbol: CD47///MER6
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基因ID
- 961
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UniProt
- Q08722
抗原
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