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CD22 抗体

This anti-CD22 antibody is a 小鼠 单克隆 antibody detecting CD22 in FACS, IF 和 Func. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6296528
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CD22 抗体 (ABIN6296528)

抗原

See all CD22 抗体
CD22 (CD22 Molecule (CD22))

适用

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人, 小鼠, 大鼠

宿主

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小鼠

克隆类型

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单克隆

标记

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This CD22 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunofluorescence (IF), Functional Studies (Func)
  • 原理

    Mouse anti-Human/Mouse/Rat CD22 Antibody [Sodium Azide Free]

    特异性

    Cell surface

    纯化方法

    Human Raji cells were used as the immunogen for the CD22 antibody.

    免疫原

    Human Raji cells were used as the immunogen for the CD22 antibody.
  • 应用备注

    Functional Activity (Order SAF formulation)
    Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
    Immunofluorescence: 0.5-1 μg/mL

    限制

    仅限研究用
  • 缓冲液

    In 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    4 °C,-20 °C

    储存方法

    2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
  • 抗原

    CD22 (CD22 Molecule (CD22))

    别名

    B-cell receptor CD22

    背景

    Target Description: Recognizes a protein of 130-140 kDa, identified as CD22 (also known as BL-CAM). CD22 expression is restricted to normal and neoplastic B cells and is absent from other haemopoietic cell types. In B-cell ontogeny, CD22 is first expressed in the cytoplasm of pro-B and pre-B cells, and on the surface as B cells mature to become IgD+. It is not expressed by plasma cells, CD22 is found highly expressed in follicular mantle and marginal zone B-cells, and while germinal center B-cells are relatively weak. CD22 is a member of the immunoglobulin superfamily and serves as an adhesion receptor for sialic acid-bearing ligands expressed on erythrocytes and all leukocyte classes. It also associates with tyrosine kinases and play a role in signal transduction and B-cell activation.

    Gene Symbol: CD22///SIGLEC2

    基因ID

    933

    UniProt

    P20273
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