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hCG Intact 抗体 (CF®640R)

This anti-hCG Intact antibody is a 小鼠 单克隆 antibody detecting hCG Intact in IHC (f). Suitable for 人.
产品编号 ABIN6165769
发货至: 中国
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Quick Overview for hCG Intact 抗体 (CF®640R) (ABIN6165769)

抗原

hCG Intact

适用

宿主

  • 10
  • 1
小鼠

克隆类型

  • 10
  • 1
单克隆

标记

  • 4
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
CF®640R

应用范围

  • 8
  • 1
  • 1
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  • 1
Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

克隆位点

HCGab-52
  • 原理

    Mouse Monoclonal anti-HCG intact (HCGab/52), CF640R Conjugate

    产品特性

    This MAb is a very special because it reacts ONLY with the intact-HCG and not with either free alpha- or free beta-chain of HCG. HCG is a glycoprotein and is composed of two non-identical, non-covalently linked polypeptide chains designated as the ? ? and ? ? subunits. The ? ? subunit is identical to that of thyroid stimulating hormone (TSH), follicle stimulating hormone (FSH), and luteinizing hormone (LH). HCG is secreted in large quantities by normal trophoblasts. It is present only in trace amounts in non-pregnant urine and sera but rises sharply during pregnancy. HCG MAb detects cells and tumors of trophoblastic origin such as choriocarcinoma. Large cell carcinoma and adenocarcinoma of the lung demonstrate anti-hCG positivity in 90 % and 60 % of cases respectively. 20 % of lung squamous cell carcinomas are positive. HCG expression by non-trophoblastic tumors may indicate aggressive behavior. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    免疫原

    Purified hCG protein

    亚型

    IgG1 kappa
  • 应用备注

    Immunohistology formalin-fixed 0.5-1 μg/mL
    • Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer,  pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes
    • Optimal dilution for a specific application should be determined by user

    说明

    JAR or TT Cells. Placenta

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    100 μg/mL

    缓冲液

    PBS/0.1 % BSA/0.05 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from light
  • 抗原

    hCG Intact

    分子量

    ~35 kDa (intact hCG)

    基因ID

    1081, 1082
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