CD2AP 抗体
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北京 101111
Quick Overview for CD2AP 抗体 (ABIN5647746)
抗原
See all CD2AP (Cd2ap) 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Antigen affinity purified
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免疫原
- A recombinant human protein corresponding to amino acids K253-K337 was used as the immunogen for the CD2AP antibody.
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亚型
- IgG
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应用备注
- Optimal dilution of the CD2AP antibody should be determined by the researcher.\. Western Blot: 0.5-1 μg/mL,FACS: 1-3 μg/10^6 cells,Direct ELISA: 0.1-0.5 μg/mL
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限制
- 仅限研究用
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- -20 °C
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储存方法
- After reconstitution, the CD2AP antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- CD2AP (Cd2ap) (CD2-Associated Protein (Cd2ap))
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别名
- CD2AP
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背景
- CD2-associated protein is a protein that in humans is encoded by the CD2AP gene. This gene encodes a scaffolding molecule that regulates the actin cytoskeleton. The protein directly interacts with filamentous actin and a variety of cell membrane proteins through multiple actin binding sites, SH3 domains, and a proline-rich region containing binding sites for SH3 domains. The cytoplasmic protein localizes to membrane ruffles, lipid rafts, and the leading edges of cells. It is implicated in dynamic actin remodeling and membrane trafficking that occurs during receptor endocytosis and cytokinesis. Haploinsufficiency of this gene is implicated in susceptibility to glomerular disease.
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UniProt
- Q9Y5K6
抗原
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