TIAM1 抗体
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北京 101111
Quick Overview for TIAM1 抗体 (ABIN5541409)
抗原
See all TIAM1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody clone F5S F6.2 is directed against the N-terminal region of Tiam1.
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纯化方法
- Purified
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免疫原
- T-cell lymphoma invasion and metastasis-inducing protein 1 (Tiam1).
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亚型
- IgG2b
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应用备注
- Western Blot. Immunohistochemistry on Frozen Sections.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Buffer System: PBS Preservatives: 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
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有效期
- 12 months
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- TIAM1 (T-Cell Lymphoma Invasion and Metastasis 1 (TIAM1))
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别名
- tiam1
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背景
- Tiam1, also known as T-cell lymphoma invasion and metastasis-inducing protein 1, is a protein that in humans is encoded by the TIAM1 gene. TIAM1 is tightly associate with BAIAP2 as a subunit. It contains one DH (DBL-homology) domain, one PDZ domain, two PH domains and one Ras-binding RBD domain. TIAM1 modulates the activity of Rho GTP-binding proteins and connects extracellular signals to cytoskeletal activities. In addition, TIAM1 activates Rac1, CDC42, and to a lesser extent RhoA. TIAM1 is found in virtually all tumor cell lines examined including B- and T-lymphomas, neuroblastomas, melanomas and carcinomas.
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UniProt
- Q13009
抗原
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