IL-11 抗体 (AA 25-199)
Quick Overview for IL-11 抗体 (AA 25-199) (ABIN5519008)
抗原
See all IL-11 (IL11) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 25-199
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原理
- Anti-IL11 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-IL11 Antibody Picoband® (ABIN5519008). Tested in ELISA, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E. coli-derived rat IL11 recombinant protein (Position: P25-L199).
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亚型
- IgG
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anti-Interleukin 11 (IL11) (AA 22-199) antibody
IL11 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 11 (IL11) (AA 22-120) antibodyIL11 适用: 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 11 (IL11) (AA 27-61) antibodyIL11 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB56890 unconjugated
anti-Interleukin 11 (IL11) antibody (Biotin)IL11 适用: 人 WB, ELISA, Neut 宿主: 兔 Polyclonal Biotin
anti-Interleukin 11 (IL11) (AA 25-74) antibodyIL11 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1F1 unconjugated
anti-Interleukin 11 (IL11) (AA 25-199) antibodyIL11 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 11 (IL11) (N-Term) antibodyIL11 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL
ELISA, 0.1-0.5 μg/mL
1. Chen, Q., Rabach, L., Noble, P., Zheng, T., Lee, C. G., Homer, R. J., Elias, J. A. IL-11 receptor alpha in the pathogenesis of IL-13-induced inflammation and remodeling. J. Immun. 174: 2305-2313, 2005. 2. McKinley, D., Wu, Q., Yang-Feng, T., Yang, Y.-C. Genomic sequence and chromosomal location of human interleukin-11 gene (IL11). Genomics 13: 814-819, 1992. -
说明
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We recommend Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- IL-11 (IL11) (Interleukin 11 (IL11))
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别名
- Il11
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背景
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Synonyms: Interleukin-11, IL-11, Il11,
Tissue Specificity: Heart. The fetal heart shows a greater expression in the atrium than in the ventricle, while the adult heart shows a greater expression in the ventricle than in the atrium. Isoform 6 predominates in normal adult heart. Isoforms 1, 7 and 8 are expressed in fetal heart. Isoform 7 is also expressed in failing adult heart.
Background: Interleukin 11 (IL-11) is a protein that in humans is encoded by the IL11 gene. The protein encoded by this gene is a member of the gp130 family of cytokines. This gene is mapped to 19q13.42. It is a key regulator of multiple events in hematopoiesis, most notably the stimulation of megakaryocyte maturation. IL-11 has been demonstrated to improve platelet recovery after chemotherapy-induced thrombocytopenia, induce acute phase proteins, modulate antigen-antibody responses, participate in the regulation of bone cell proliferation and differentiation and could be use as a therapeutic for osteoporosis. What's more, IL-11 can stimulate the growth of certain lymphocytes and it has functions in many other tissues, including the brain, gut, testis and bone. In transgenic mice, overexpression of the human IL11 gene resulted in the stimulation of bone formation to increase cortical thickness and strength of long bones.
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分子量
- 21 kDa
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基因ID
- 171040
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途径
- JAK/STAT Signaling, Negative Regulation of Hormone Secretion
抗原
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