ADCY5 抗体
Quick Overview for ADCY5 抗体 (ABIN498295)
抗原
See all ADCY5 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects endogenous levels of A Cyclase V/VI protein. (region surrounding Phe1052)
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交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.
Also reacts to: ADCY6 -
纯化方法
- Affinity Chromatography using epitope-specific immunogen
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anti-Adenylate Cyclase 5 (ADCY5) (AA 1152-1261) antibody
ADCY5 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3E6 unconjugated
anti-Adenylate Cyclase 5 (ADCY5) (AA 857-909) antibodyADCY5 适用: 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Adenylate Cyclase 5 (ADCY5) antibodyADCY5 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Adenylate Cyclase 5 (ADCY5) (AA 584-719) antibodyADCY5 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Adenylate Cyclase 5 (ADCY5) (AA 604-639) antibodyADCY5 适用: 人 WB 宿主: 兔 Polyclonal RB53332 unconjugated
anti-Adenylate Cyclase 5 (ADCY5) (AA 1152-1261) antibodyADCY5 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Adenylate Cyclase 5 (ADCY5) (AA 167-385) antibodyADCY5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 -1/200. Immunofluorescence: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- ADCY5 (Adenylate Cyclase 5 (ADCY5))
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别名
- Adenylate Cyclase Type 5
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背景
- A cyclase V, also known as ADCY5, is a 1,261 amino acid Adenylyl cyclase that localizes to cellular membranes and contains two guanylate cyclase domains. Similar to other A cyclase proteins, A cyclase V uses magnesium as a cofactor to catalyze the conversion of ATP to cAMP. A cyclase VI, also known as ADCY6 (adenylate cyclase type 6), is a 1,168 amino acid A cyclase that localizes to the membrane and contains two guanylate cyclase domains. Using magnesium as a cofactor, A cyclase VI functions as a calcium-inhibitable A cyclase that catalyzes the conversion of ATP to 3',5'-cyclic AMP and diphosphate and plays a role in a variety of events throughout the body. Multiple isoforms of A cyclase VI exist due to alternative splicing events.Synonyms: ADCY5, ATP pyrophosphate-lyase 5, Adenylate cyclase type V, Adenylyl cyclase 5
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分子量
- approx. 138 kDa
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基因ID
- 111
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NCBI登录号
- NP_899200
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UniProt
- O95622
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途径
- EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, cAMP Metabolic Process, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma
抗原
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