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ADCY5 抗体

This anti-ADCY5 antibody is a 兔 多克隆 antibody detecting ADCY5 in WB, IF 和 IHC (p). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN498295
发货至: 中国
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Quick Overview for ADCY5 抗体 (ABIN498295)

抗原

See all ADCY5 抗体
ADCY5 (Adenylate Cyclase 5 (ADCY5))

适用

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人, 小鼠, 大鼠

宿主

  • 38
  • 4

克隆类型

  • 39
  • 3
多克隆

标记

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  • 1
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  • 1
  • 1
  • 1
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This ADCY5 antibody is un-conjugated

应用范围

  • 30
  • 14
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  • 6
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Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 特异性

    This antibody detects endogenous levels of A Cyclase V/VI protein. (region surrounding Phe1052)

    交叉反应 (详细)

    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.
    Also reacts to: ADCY6

    纯化方法

    Affinity Chromatography using epitope-specific immunogen
  • 应用备注

    Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 -1/200. Immunofluorescence: 1/50 - 1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Phosphate buffered saline (PBS), pH 7.2., 0.05 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    ADCY5 (Adenylate Cyclase 5 (ADCY5))

    别名

    Adenylate Cyclase Type 5

    背景

    A cyclase V, also known as ADCY5, is a 1,261 amino acid Adenylyl cyclase that localizes to cellular membranes and contains two guanylate cyclase domains. Similar to other A cyclase proteins, A cyclase V uses magnesium as a cofactor to catalyze the conversion of ATP to cAMP. A cyclase VI, also known as ADCY6 (adenylate cyclase type 6), is a 1,168 amino acid A cyclase that localizes to the membrane and contains two guanylate cyclase domains. Using magnesium as a cofactor, A cyclase VI functions as a calcium-inhibitable A cyclase that catalyzes the conversion of ATP to 3',5'-cyclic AMP and diphosphate and plays a role in a variety of events throughout the body. Multiple isoforms of A cyclase VI exist due to alternative splicing events.Synonyms: ADCY5, ATP pyrophosphate-lyase 5, Adenylate cyclase type V, Adenylyl cyclase 5

    分子量

    approx. 138 kDa

    基因ID

    111

    NCBI登录号

    NP_899200

    UniProt

    O95622

    途径

    EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, cAMP Metabolic Process, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma
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