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Dityrosine 抗体

DT WB, EIA, IHC (p) 宿主: 小鼠 Monoclonal 1C3 unconjugated
产品编号 ABIN492669
发货至: 中国
  • 抗原 See all Dityrosine (DT) products
    Dityrosine (DT)
    宿主
    • 11
    小鼠
    克隆类型
    • 11
    单克隆
    标记
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Dityrosine antibody is un-conjugated
    应用范围
    • 11
    • 11
    • 10
    • 10
    • 10
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    Protein A Chromatography
    免疫原
    3-(p-hydroxyphenyl) propionic acid dimer KLH-conjugated
    克隆位点
    1C3
    亚型
    IgG2a
  • 应用备注
    ELISA (Ref.1,2)Western bLot (Ref.3,5)Immunohistochemistry on Paraffin Sections (Ref.4).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 溶解方式
    Restore in 200 μL aqua bidest to 0.1 mg/mL
    储存条件
    -20 °C
    储存方法
    Store the antibody at -20 °CAfter reconstitution, store as frozen aliquotsAvoid repeated freezing and thawingShelf life: One year from despatch.
    有效期
    12 months
  • Li, Shi, Ding, Ran, Le: "Dietary oxidized tyrosine (O-Tyr) stimulates TGF-β1-induced extracellular matrix production via the JNK/p38 signaling pathway in rat kidneys." in: Amino acids, Vol. 49, Issue 2, pp. 241-260, (2018) (PubMed).

  • 抗原
    Dityrosine (DT)
    别名
    Dityrosine / DT (DT 产品)
    物质类
    Dipeptide
    背景
    Tyrosine is one of the major targets of protein oxidation, and until today various tyrosine derivatives such as nitrotyrosine, dityrosine and halogenated tyrosine depending on the type of free radicals. DT is a tyrosine dimer derived from tyrosyl radicals which is formed by reactive oxygen species (ROS), metal-catalyzed oxidation, ultraviolet irradiation, and peroxidases. DT have been found in atherosclerotic lesions, and lipofuscin of pyramidal neurons of aged human brains. Dityrosine is one of the specific biomarkers for protein oxidation.
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