VNN1 抗体 (AA 22-192)
Quick Overview for VNN1 抗体 (AA 22-192) (ABIN4886761)
抗原
See all VNN1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 22-192
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原理
- Anti-VNN1 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-VNN1 Antibody Picoband® (ABIN4886761). Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E. coli-derived human VNN1 recombinant protein (Position: Q22-K192). Human VNN1 shares 82.2% amino acid (aa) sequence identity with mouse VNN1.
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亚型
- IgG
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anti-Vanin 1 (VNN1) (AA 389-497) antibody
VNN1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Vanin 1 (VNN1) (AA 36-223) antibodyVNN1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Vanin 1 (VNN1) (AA 97-197) antibodyVNN1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Vanin 1 (VNN1) (AA 22-328) antibodyVNN1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Vanin 1 (VNN1) (AA 1-513) antibodyVNN1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Vanin 1 (VNN1) (AA 298-397) antibodyVNN1 适用: 人 ELISA, IF 宿主: 小鼠 Monoclonal 4E11 unconjugated
anti-Vanin 1 (VNN1) (AA 298-397) antibodyVNN1 适用: 人 IP, ELISA 宿主: 小鼠 Monoclonal 2B10 unconjugated
anti-Vanin 1 (VNN1) (AA 300-415) antibodyVNN1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Vanin 1 (VNN1) (AA 151-250) antibodyVNN1 适用: 人, 小鼠, 大鼠 WB, ELISA, ICC, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Vanin 1 (VNN1) (AA 216-469) antibodyVNN1 适用: Cow WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human
1. "Entrez Gene: VNN1 vanin 1". 2. Galland F, Malergue F, Bazin H, Mattei MG, Aurrand-Lions M, Theillet C, Naquet P (Dec 1998). "Two human genes related to murine vanin-1 are located on the long arm of human chromosome 6". Genomics 53 (2): 203-13. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- VNN1 (Vanin 1 (VNN1))
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别名
- VNN1
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背景
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Synonyms: Pantetheinase,3.5.1.92 ,Pantetheine hydrolase,Tiff66,Vascular non-inflammatory molecule 1,Vanin-1,VNN1,
Tissue Specificity: Widely expressed with higher expression in spleen, kidney and blood. Overexpressed in lesional psoriatic skin. .
Background: Pantetheinase is an enzyme that in humans is encoded by the VNN1 gene. This gene encodes a member of the vanin family of proteins, which share extensive sequence similarity with each other, and also with biotinidase. The family includes secreted and membrane-associated proteins, a few of which have been reported to participate in hematopoietic cell trafficking. No biotinidase activity has been demonstrated for any of the vanin proteins, however, they possess pantetheinase activity, which may play a role in oxidative-stress response. This protein, like its mouse homolog, is likely a GPI-anchored cell surface molecule. The mouse protein is expressed by the perivascular thymic stromal cells and regulates migration of T-cell progenitors to the thymus. This gene lies in close proximity to, and in the same transcriptional orientation as, two other vanin genes on chromosome 6q23-q24.
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分子量
- 57 kDa
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基因ID
- 8876
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UniProt
- O95497
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途径
- Negative Regulation of intrinsic apoptotic Signaling
抗原
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