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CD3 抗体 (APC)

CD3 适用: 小鼠 FACS 宿主: 仓鼠 Monoclonal 145-2C11 APC
产品编号 ABIN487429
发货至: 中国
  • 抗原 See all CD3 抗体
    CD3
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    仓鼠
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    单克隆
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    This CD3 antibody is conjugated to APC
    应用范围
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    Flow Cytometry (FACS)
    特异性
    This antibody reacts with mouse CD3 (epsilon subunit). It is commonly used as a phenotypic marker for mouse T cells.
    交叉反应 (详细)
    Species reactivity (tested):Mouse
    产品特性
    Synonyms: T3/Leu-4, T-cell surface glycoprotein CD3, T-cell surface antigen T3/Leu-4
    免疫原
    Mouse BM10-37 cytotoxic T lymphocytes
    克隆位点
    145-2C11
    亚型
    IgG
    Top Product
    Discover our top product CD3 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Phosphate buffered saline (PBS) containing 15 mM sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store the antibody at 2 - 8 °C. DO NOT FREEZE! This product is photosensitive and should be protected from light.
    Shelf life: one year from despatch.
    有效期
    12 months
  • 抗原
    CD3
    别名
    CD3 (CD3 产品)
    背景
    CD3 complex is crucial in transducing antigen-recognition signals into the cytoplasm of T cells and in regulating the cell surface expression of the TCR complex. T cell activation through the antigen receptor (TCR) involves the cytoplasmic tails of the CD3 subunits CD3 gamma, CD3 delta, CD3 epsilon and CD3 zeta. These CD3 subunits are structurally related members of the immunoglobulins superfamily encoded by closely linked genes on human chromosome 11. The CD3 components have long cytoplasmic tails that associate with cytoplasmic signal transduction molecules. This association is mediated at least in part by a double tyrosine-based motif present in a single copy in the CD3 subunits. CD3 may play a role in TCR-induced growth arrest, cell survival and proliferation.Synonyms: T-cell surface antigen T3/Leu-4, T-cell surface glycoprotein CD3, T3/Leu-4
    基因ID
    12501
    UniProt
    P22646
    途径
    TCR Signaling, Ubiquitin Proteasome Pathway
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