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CD3 抗体 (APC)

This anti-CD3 antibody is a 仓鼠 单克隆 antibody detecting CD3 in FACS. Suitable for 小鼠.
产品编号 ABIN487429
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CD3 抗体 (APC) (ABIN487429)

抗原

See all CD3 抗体
CD3

适用

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小鼠

宿主

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仓鼠

克隆类型

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单克隆

标记

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This CD3 antibody is conjugated to APC

应用范围

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Flow Cytometry (FACS)

克隆位点

145-2C11
  • 特异性

    This antibody reacts with mouse CD3 (epsilon subunit). It is commonly used as a phenotypic marker for mouse T cells.

    交叉反应 (详细)

    Species reactivity (tested):Mouse

    产品特性

    Synonyms: T3/Leu-4, T-cell surface glycoprotein CD3, T-cell surface antigen T3/Leu-4

    免疫原

    Mouse BM10-37 cytotoxic T lymphocytes

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    Phosphate buffered saline (PBS) containing 15 mM sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store the antibody at 2 - 8 °C. DO NOT FREEZE! This product is photosensitive and should be protected from light.
    Shelf life: one year from despatch.

    有效期

    12 months
  • 抗原

    CD3

    别名

    CD3

    背景

    CD3 complex is crucial in transducing antigen-recognition signals into the cytoplasm of T cells and in regulating the cell surface expression of the TCR complex. T cell activation through the antigen receptor (TCR) involves the cytoplasmic tails of the CD3 subunits CD3 gamma, CD3 delta, CD3 epsilon and CD3 zeta. These CD3 subunits are structurally related members of the immunoglobulins superfamily encoded by closely linked genes on human chromosome 11. The CD3 components have long cytoplasmic tails that associate with cytoplasmic signal transduction molecules. This association is mediated at least in part by a double tyrosine-based motif present in a single copy in the CD3 subunits. CD3 may play a role in TCR-induced growth arrest, cell survival and proliferation.Synonyms: T-cell surface antigen T3/Leu-4, T-cell surface glycoprotein CD3, T3/Leu-4

    基因ID

    12501

    UniProt

    P22646

    途径

    TCR Signaling, Ubiquitin Proteasome Pathway
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