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ITGAL 抗体

This anti-ITGAL antibody is a 大鼠 单克隆 antibody detecting ITGAL in FACS, IP, Func 和 IHC (fro). Suitable for 小鼠.
产品编号 ABIN452277
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for ITGAL 抗体 (ABIN452277)

抗原

See all ITGAL 抗体
ITGAL (Integrin alpha-L (ITGAL))

适用

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小鼠

宿主

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大鼠

克隆类型

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单克隆

标记

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This ITGAL antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunoprecipitation (IP), Functional Studies (Func), Immunohistochemistry (Frozen Sections) (IHC (fro))

克隆位点

M17-4
  • 交叉反应 (详细)

    Species reactivity (tested):Mouse.

    产品特性

    Synonyms: Integrin alpha-L, LFA1, LFA-1, Leukocyte adhesion glycoprotein LFA-1 alpha chain, Leukocytefunction-associated molecule 1 alpha chain, CD11 antigen-like family member A

    纯化方法

    Protein-G affinity chromatography

    免疫原

    C57BL/6 mouse splenic secondary cytotoxic T lymphocytes

    亚型

    IgG2a
  • 应用备注

    Flow cytometry: 1 μg/mL. Immunoprecipitation. Immunohistochemistry on frozen sections: acetone fixation (Positive tissue: mouse spleenor thymus). Functional application. Blocking.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS, pH ~7.4, 15 mM Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoidrepeated freezing and thawing.
    Shelf life: one year from despatch.

    有效期

    12 months
  • 抗原

    ITGAL (Integrin alpha-L (ITGAL))

    别名

    CD11a / ITGAL

    背景

    CD11a (LFA-1 alpha) together with CD18 constitute leukocyte function-associated antigen 1 (LFA-1), the alphaLbeta2 integrin. CD11a is implicated in activation of LFA-1 complex. LFA-1 is expressed on the plasma membrane of leukocytes in a low-affinity conformation. Cell stimulation by chemokines or other signals leads to induction the high-affinity conformation, which supports tight binding of LFA-1 to its ligands, the intercellular adhesion molecules ICAM-1, -2, -3. LFA-1 is thus involved in interaction of various immune cells and in their tissue-specific settlement, but participates also in control of cell differentiation and proliferation and of T-cell effector functions.Synonyms: CD11 antigen-like family member A, Integrin alpha-L, LFA-1, LFA1, Leukocyte adhesion glycoprotein LFA-1 alpha chain, Leukocyte function-associated molecule 1 alpha chain

    UniProt

    P24063

    途径

    Activated T Cell Proliferation, Integrin Complex
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