CD8B 抗体
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北京 101111
Quick Overview for CD8B 抗体 (ABIN371369)
抗原
See all CD8B 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody recognizes beta chain of Chicken CD8 (Mr. 34 kDa).
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产品特性
- Synonyms: eu2, Ly3, LYT3, CD8B1, T cell surface glycoprotein CD8 beta chain
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纯化方法
- Purified
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亚型
- IgG2a
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应用备注
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Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- 100 mM Borate Buffered Saline, pH 8.2. No preservatives or amine-containing buffer salts added.
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储存条件
- 4 °C/-20 °C
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储存方法
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
有效期
- 12 months
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- CD8B (CD8b Molecule (CD8B))
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别名
- CD8 beta
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背景
- The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell to cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. Chicken CD8 is expressed on approximately 80 % of thymocytes, 45 % of blood mononuclear cells and 50 % of spleen cells, but <1 % of cells in the bursa and bone marrow. (Ref.1,2)Synonyms: CD8B, CD8B1, T-cell surface glycoprotein CD8 beta chain
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基因ID
- 396175
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UniProt
- Q90769
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途径
- TCR Signaling
抗原
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