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CD3 抗体 (FITC)

CD3 适用: 小鼠 FACS 宿主: 大鼠 Monoclonal C363-29B (YCD3-1) FITC
产品编号 ABIN356218
发货至: 中国
  • 抗原 See all CD3 抗体
    CD3
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    大鼠
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    This CD3 antibody is conjugated to FITC
    应用范围
    • 288
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    Flow Cytometry (FACS)
    特异性
    This antibody is specific to CD3e (Mr. 25 kDa).
    产品特性
    Synonyms: T3/Leu-4, T-cell surface glycoprotein CD3, T-cell surface antigen T3/Leu-4
    克隆位点
    C363-29B (YCD3-1)
    亚型
    IgG2b
    Top Product
    Discover our top product CD3 Primary Antibody
  • 应用备注
    Flow Cytometry: Identification and enumeration of CD3+ (< / = 3 μg/10^6 cells). (Ref.1,2).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    PBS containing 0.09 % Sodium Azide as preservative.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.
    有效期
    12 months
  • 抗原
    CD3
    别名
    CD3 (CD3 产品)
    背景
    CD3e, a member of the immunoglobulin superfamily of cell surface receptors, is comprised of five invariable chain ranging in size from 16-28 kDa and is closely associated with the T cell antigen receptor (TCR). It is expressed on all T cells of all mouse strains. (Ref.1,2) CD3 plays a major role in signaling during antigen recognition, leading to T-cell activation. The monoclonal antibody C363.29B recognizes an epitope on the 25kD epsilon chain of the CD3/TCR complex. (Ref.1) In the presence of Fc receptor-bearing accessory cells, soluble C363.29B can activate primed and naive T cell in vitro. Immobilized C363.29 monoclonal antibody can also activate both normal T lymphocytes and cloned T cell lines provided the appropriate accessory signals are present. (Ref.1,3,4) The monoclonal antibody is cytolytic, easily used for cell surface staining and a good immunoprecipitating antibody. (Ref.1)Synonyms: T-cell surface antigen T3/Leu-4, T-cell surface glycoprotein CD3, T3/Leu-4
    基因ID
    12501
    UniProt
    P22646
    途径
    TCR Signaling, Ubiquitin Proteasome Pathway
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