Ataxin 2 抗体 (C-Term)
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- 抗原 See all Ataxin 2 (ATXN2) 抗体
- Ataxin 2 (ATXN2)
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抗原表位
- AA 1283-1313, C-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Ataxin 2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 原理
- Anti-ATX2/ATXN2 Antibody Picoband®
- 序列
- QSALQPIPVS TTAHFPYMTH PSVQAHHQQQ L
- 交叉反应 （详细）
- No cross-reactivity with other proteins
- 产品特性
- Anti-ATX2/ATXN2 Antibody Picoband® (ABIN3043507). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
- 纯化方法
- Immunogen affinity purified.
- 免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human ATX2, identical to the related mouse sequence.
- 亚型
- IgG
- Top Product
- Discover our top product ATXN2 Primary Antibody
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anti-Ataxin 2 (ATXN2) (C-Term) antibody
ATXN2 适用: 人, 小鼠, 大鼠 WB, IF, ICC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Ataxin 2 (ATXN2) (AA 775-856) antibodyATXN2 适用: 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Ataxin 2 (ATXN2) (Internal Region) antibodyVerified ATXN2 适用: 人 ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Ataxin 2 (ATXN2) (AA 174-383) antibodyATXN2 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Ataxin 2 (ATXN2) (Internal Region) antibodyATXN2 适用: 人 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ataxin 2 (ATXN2) (AA 321-355) antibodyATXN2 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB53600 unconjugated
anti-Ataxin 2 (ATXN2) (AA 725-757) antibodyATXN2 适用: 人 WB 宿主: 兔 Polyclonal RB53601 unconjugated
anti-Ataxin 2 (ATXN2) (AA 1214-1313) antibodyATXN2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Ataxin 2 (ATXN2) (Middle Region) antibodyATXN2 适用: 人, 小鼠, Cow, 犬 WB 宿主: 兔 Polyclonal unconjugated
anti-Ataxin 2 (ATXN2) (Middle Region) antibodyATXN2 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 豚鼠, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human
1. Pulst, S.-M., Nechiporuk, A., Nechiporuk, T., Gispert, S., Chen, X.-N., Lopes-Cendes, I., Pearlman, S., Starkman, S., Orozco-Diaz, G., Lunkes, A., DeJong, P., Rouleau, G. A., Auburger, G., Korenberg, J. R., Figueroa, C., Sahba, S. Moderate expansion of a normally biallelic trinucleotide repeat in spinocerebellar ataxia type 2. 2. Ralser, M., Nonhoff, U., Albrecht, M., Lengauer, T., Wanker, E. E., Lehrach, H., Krobitsch, S. Ataxin-2 and huntingtin interact with endophilin-A complexes to function in plastin-associated pathways. Hum. Molec. Genet. 14: 2893-2909, 2005. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- 抗原
- Ataxin 2 (ATXN2)
- 别名
- ATXN2 (ATXN2 产品)
- 背景
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Synonyms: Ataxin-2,Spinocerebellar ataxia type 2 protein,Trinucleotide repeat-containing gene 13 protein,ATXN2,ATX2, SCA2, TNRC13,
Tissue Specificity: Expressed in the brain, heart, liver, skeletal muscle, pancreas and placenta. Isoform 1 is predominant in the brain and spinal cord. Isoform 4 is more abundant in the cerebellum. In the brain, broadly expressed in the amygdala, caudate nucleus, corpus callosum, hippocampus, hypothalamus, substantia nigra, subthalamic nucleus and thalamus. .
Background: Ataxin-2, the protein encoded by the ATXN2 gene, contains a polyglutamine tract, long expansions (greater than 33 repeats) of which result in spinocerebellar ataxia-2 (SCA2), an autosomal dominant form of olivopontocerebellar atrophy. The gene for spinocerebellar ataxia type 2 (SCA2) has been mapped to 12q24.1. Ataxin-2 associates with L- and T-plastin and that overexpression of ataxin-2 leads to accumulation of T-plastin in mammalian cells.
Sequence Similarities: Belongs to the ATG14 family.
- 分子量
- 140 kDa
- UniProt
- Q99700
- 途径
- Ribonucleoprotein Complex Subunit Organization
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