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CD16 抗体 (Biotin)

CD16 适用: 人 FACS 宿主: 小鼠 Monoclonal MEM-154 Biotin
产品编号 ABIN303523
发货至: 中国
  • 抗原 See all CD16 抗体
    CD16
    适用
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    小鼠
    克隆类型
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    单克隆
    标记
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    This CD16 antibody is conjugated to Biotin
    应用范围
    • 133
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    Flow Cytometry (FACS)
    特异性
    This antibody reacts with the epitope on CD16 antigen that residing in proximity to FG loop (probably BC or C'E loop). CD16 is a low affinity receptor for aggregated IgG (FcgRIII antigen). The antibody reacts with CD16+ granulocytes.
    免疫原
    Human granulocytes
    克隆位点
    MEM-154
    亚型
    IgG1
    Top Product
    Discover our top product CD16 Primary Antibody
  • 应用备注
    Flow cytometry: starting point for use in indirect immunoflourescence is 1:500.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS, pH ~7.4 with 15 mM Sodium Azide as preservative.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
    Shelf Life: one year from despatch.
    有效期
    12 months
  • 抗原
    CD16
    别名
    CD16 (CD16 产品)
    背景
    CD16 (FcgRIII) is a 50-65 kDa glycoprotein serving as a low affinity IgG receptor. Human FcgRIII is expressed in two forms FcgRIII-A and -B. FcgRIII-A is a transmembrane protein of monocytes, macrophages, NK cells and a subset of T cells. It is associated with FceRI-g subunit and is responsible for antibody-dependent NK cell cytotoxicity. Mast cell FcgRIII-A is associated, moreover, with FceRI-b subunit. Besides IgG, FceRI-A can be triggered also by oligomeric IgE. FcgRIII-B is a GPI-linked monomeric receptor expressed on neutrophils and is involved in their activation and induction of a proadhesive phenotype.Synonyms: CD16A, FCG3, FCGR3, FCGR3A, Fc-gamma RIII, Fc-gamma RIII-alpha, Fc-gamma RIIIa, FcR-10, FcRIII, FcRIIIa, IGFR3, IgG Fc receptor III-2, Low affinity immunoglobulin gamma Fc region receptor III-A
    基因ID
    2214
    UniProt
    P08637
    途径
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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