Prolactin Receptor 抗体 (C-Term)
Quick Overview for Prolactin Receptor 抗体 (C-Term) (ABIN3032320)
抗原
See all Prolactin Receptor (PRLR) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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纯化方法
- Antigen affinity
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免疫原
- An amino acid sequence from the C-terminus of mouse Prolactin Receptor (QLGRLDYLDPTCFMH) was used as the immunogen for this Prolactin Receptor antibody (100% rat homology).
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亚型
- IgG
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anti-Prolactin Receptor (PRLR) (AA 25-234) antibody
PRLR 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Prolactin Receptor (PRLR) (AA 20-229) antibodyPRLR 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Prolactin Receptor (PRLR) (AA 591-605), (C-Term) antibodyPRLR 适用: 人, 大鼠, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Prolactin Receptor (PRLR) (AA 1-622) antibodyPRLR 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Prolactin Receptor (PRLR) (AA 371-479) antibodyPRLR 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1E4 unconjugated
anti-Prolactin Receptor (PRLR) antibodyPRLR 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal rPRLR-742 unconjugated Recombinant Antibody
anti-Prolactin Receptor (PRLR) (AA 251-350) antibodyPRLR 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Prolactin Receptor (PRLR) antibodyPRLR 适用: 人 IHC, StM 宿主: 兔 Monoclonal PRLR-3785R unconjugated Recombinant Antibody
anti-Prolactin Receptor (PRLR) (AA 330-548) antibodyPRLR 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Prolactin Receptor (PRLR) antibodyPRLR 适用: 人 FACS 宿主: 兔 Chimeric unconjugated Fc fragment
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应用备注
- The stated application concentrations are suggested starting amounts. Titration of the Prolactin Receptor antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL
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限制
- 仅限研究用
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- -20 °C
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储存方法
- After reconstitution, the Prolactin Receptor antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- Prolactin Receptor (PRLR)
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别名
- Prolactin Receptor
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背景
- PRLR (Prolactin Receptor) is a cytokine receptor. By somatic cell hybrid analysis and by in situ hybridization, Arden et al.(1989, 1990) demonstrated that the gene resides in the same chromosomal region as the growth hormone receptor (GHR) gene, which has been mapped to 5p13-p12. Cunningham et al.(1990) demonstrated that zinc greatly increases the affinity of GH for the extracellular binding domain of PRLR, although it is not required for binding of GH to GHR or for binding of prolactin to the prolactin receptor. By mutational analysis, they showed that a cluster of 3 residues(histidine-18, histidine-21, and glutamic acid-174) in GH and histidine-188 in PRLR (conserved in all PRLRs but not GHRs) are likely zinc-ion ligands.
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UniProt
- Q08501
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途径
- JAK/STAT Signaling, Response to Growth Hormone Stimulus
抗原
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