PFN2 抗体 (C-Term)
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Quick Overview for PFN2 抗体 (C-Term) (ABIN3032305)
抗原
See all PFN2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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纯化方法
- Antigen affinity
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免疫原
- An amino acid sequence from the C-terminus of human PFN2 (NKKAYSMAKYLRDSGF) was used as the immunogen for this Profilin 2 antibody (100% homologous in human, mouse and rat).
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亚型
- IgG
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anti-Profilin 2 (PFN2) (AA 5-140) antibody
PFN2 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Profilin 2 (PFN2) antibodyPFN2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Profilin 2 (PFN2) (AA 41-140) antibodyPFN2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 6G3 unconjugated
anti-Profilin 2 (PFN2) (AA 125-140), (C-Term) antibodyPFN2 适用: 人, 大鼠, 小鼠 WB, IHC, ICC, FACS, IF 宿主: 兔 Polyclonal unconjugated
anti-Profilin 2 (PFN2) (AA 51-140) antibodyPFN2 适用: 人 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Profilin 2 (PFN2) (AA 1-140) antibodyPFN2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- The stated application concentrations are suggested starting amounts. Titration of the Profilin 2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL
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限制
- 仅限研究用
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- -20 °C
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储存方法
- After reconstitution, the Profilin 2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- PFN2 (Profilin 2 (PFN2))
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别名
- Profilin 2
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背景
- Profilin-2 is a protein that in humans is encoded by the PFN2 gene. The protein encoded by this gene is a ubiquitous actin monomer-binding protein belonging to the profilin family. This gene is mapped to 3q25.1. It is thought to regulate actin polymerization in response to extracellular signals. There are two alternatively spliced transcript variants encoding different isoforms described for this gene. Profilin-2 binds to actin and affects the structure of the cytoskeleton. At high concentrations, it prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG.
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UniProt
- P35080
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途径
- Regulation of Actin Filament Polymerization, Synaptic Vesicle Exocytosis
抗原
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