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PFN2 抗体 (C-Term)

This anti-PFN2 antibody is a 兔 多克隆 antibody detecting PFN2 in WB 和 IHC (p). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN3032305
发货至: 中国

Quick Overview for PFN2 抗体 (C-Term) (ABIN3032305)

抗原

See all PFN2 抗体
PFN2 (Profilin 2 (PFN2))

适用

  • 50
  • 15
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  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 49
  • 3

克隆类型

  • 49
  • 3
多克隆

标记

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  • 6
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This PFN2 antibody is un-conjugated

应用范围

  • 45
  • 15
  • 13
  • 13
  • 11
  • 6
  • 5
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 15
    • 9
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    纯化方法

    Antigen affinity

    免疫原

    An amino acid sequence from the C-terminus of human PFN2 (NKKAYSMAKYLRDSGF) was used as the immunogen for this Profilin 2 antibody (100% homologous in human, mouse and rat).

    亚型

    IgG
  • 应用备注

    The stated application concentrations are suggested starting amounts. Titration of the Profilin 2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

    限制

    仅限研究用
  • 缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    -20 °C

    储存方法

    After reconstitution, the Profilin 2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原

    PFN2 (Profilin 2 (PFN2))

    别名

    Profilin 2

    背景

    Profilin-2 is a protein that in humans is encoded by the PFN2 gene. The protein encoded by this gene is a ubiquitous actin monomer-binding protein belonging to the profilin family. This gene is mapped to 3q25.1. It is thought to regulate actin polymerization in response to extracellular signals. There are two alternatively spliced transcript variants encoding different isoforms described for this gene. Profilin-2 binds to actin and affects the structure of the cytoskeleton. At high concentrations, it prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG.

    UniProt

    P35080

    途径

    Regulation of Actin Filament Polymerization, Synaptic Vesicle Exocytosis
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