PEBP1 抗体 (N-Term)
Quick Overview for PEBP1 抗体 (N-Term) (ABIN3032217)
抗原
See all PEBP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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纯化方法
- Antigen affinity
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免疫原
- An amino acid sequence from the N-terminus of mouse PBP (QEVDEPPQHALRVDY) was used as the immunogen for this PBP antibody (100% rat homology).
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亚型
- IgG
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anti-Phosphatidylethanolamine Binding Protein 1 (PEBP1) (AA 2-187) antibody
PEBP1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Phosphatidylethanolamine Binding Protein 1 (PEBP1) (AA 2-187) antibodyPEBP1 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Phosphatidylethanolamine Binding Protein 1 (PEBP1) (C-Term) antibodyVerified PEBP1 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Phosphatidylethanolamine Binding Protein 1 (PEBP1) (C-Term) antibodyPEBP1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Phosphatidylethanolamine Binding Protein 1 (PEBP1) (AA 1-187) antibodyPEBP1 适用: 人 WB, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Phosphatidylethanolamine Binding Protein 1 (PEBP1) (AA 97-128) antibodyPEBP1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Phosphatidylethanolamine Binding Protein 1 (PEBP1) antibodyPEBP1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Phosphatidylethanolamine Binding Protein 1 (PEBP1) (AA 1-187) antibodyPEBP1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1D3-1B6 unconjugated
anti-Phosphatidylethanolamine Binding Protein 1 (PEBP1) (AA 1-30), (N-Term) antibodyPEBP1 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB3718 unconjugated
anti-Phosphatidylethanolamine Binding Protein 1 (PEBP1) (AA 137-167) antibodyPEBP1 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB3719 unconjugated
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应用备注
- The stated application concentrations are suggested starting amounts. Titration of the PBP antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL
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限制
- 仅限研究用
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- -20 °C
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储存方法
- After reconstitution, the PBP antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- PEBP1 (Phosphatidylethanolamine Binding Protein 1 (PEBP1))
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别名
- PBP
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背景
- Phosphatidylethanolamine-binding protein inhibits the phosphorylation and activation of MEK by RAF1. PBP coimmunoprecipitates with RAF1 and MEK from cell lysates and colocalizes with RAF1 when examined by confocal microscopy. Overexpression interferes with the activation of MEK and ERK, induction of AP1-dependent reporter genes, and transformation elicited by an oncogenically activated RAF1 kinase. PBP expression was rapidly upregulated during induction of chemotherapy-triggered apoptosis in human prostate and breast cancer cell lines, and maximal expression correlated perfectly with the onset of apoptosis by Chatterjee et al(2004). Depletion of the protein decreased the mitotic index, the number of metaphase cells, traversal times from nuclear envelope breakdown to anaphase, and an override of mitotic checkpoints induced by spindle poisons.
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UniProt
- P70296
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途径
- Feeding Behaviour
抗原
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