Huntingtin 抗体 (C-Term)
Quick Overview for Huntingtin 抗体 (C-Term) (ABIN3031257)
抗原
See all Huntingtin (HTT) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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纯化方法
- Antigen affinity
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免疫原
- An amino acid sequence from the C-terminus of human HTT (ELDRRAFQSVLEVVAA) was used as the immunogen for this Huntingtin antibody.
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亚型
- IgG
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anti-Huntingtin (HTT) (AA 81-190) antibody
HTT 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3F1 unconjugated
anti-Huntingtin (HTT) (AA 85-200) antibodyHTT 适用: 人, 大鼠, 小鼠, 兔, 猴, 马, 犬, 绵羊, Pig, Hamster, 豚鼠, 山羊, 驴, Cow, 小鸡, Cat, Avian WB, IF, IHC (p) 宿主: 山羊 Polyclonal unconjugated
anti-Huntingtin (HTT) (AA 81-190) antibodyHTT 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2E10 unconjugated
anti-Huntingtin (HTT) (AA 81-190) antibodyHTT 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1H6 unconjugated
anti-Huntingtin (HTT) (AA 782-920) antibodyHTT 适用: 小鼠 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Huntingtin (HTT) antibodyHTT 适用: 人 IHC, ELISA 宿主: 兔 Monoclonal 6F2 unconjugated Recombinant Antibody
anti-Huntingtin (HTT) (AA 81-191) antibodyHTT 适用: 人 IHC, WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3F1 unconjugated
anti-Huntingtin (HTT) (AA 81-190) antibodyHTT 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3F9 unconjugated
anti-Huntingtin (HTT) (AA 2703-2911) antibodyHTT 适用: 人, 兔 IHC, WB, IP, IHC (p), IHC (fro) 宿主: 小鼠 Monoclonal unconjugated
anti-Huntingtin (HTT) (AA 751-850) antibodyHTT 适用: 大鼠 ELISA, ICC, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
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应用备注
- The stated application concentrations are suggested starting amounts. Titration of the Huntingtin antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL
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限制
- 仅限研究用
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- -20 °C
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储存方法
- After reconstitution, the Huntingtin antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- Huntingtin (HTT)
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别名
- Huntingtin
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背景
- The Huntingtin gene, also called HTT or HD (Huntington disease), is the IT15 (interesting transcript 15) gene which codes for a protein called the Huntingtin. The protein has no sequence homology with other proteins and is highly expressed in neurons and tests in humans and rodents. HTT upregulates the expression of Brain Derived Neurotrophic Factor (BDNF) at the transcription level, and this gene is required for normal development. HTT is involved in vesicle trafficking as it interacts with HIP1, a clathrin-binding protein, to mediate endocytosis, the absorption of materials into a cell. HTT was also visualized as punctate staining likely to represent nerve endings. Additionally, wildtype Huntingtin may function in the nucleus in the assembly of nuclear matrix-bound protein complexes involved with transcriptional repression and RNA processing.
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UniProt
- P42858
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途径
- PI3K-Akt Signaling, Hormone Transport, Transition Metal Ion Homeostasis, Tube Formation, Protein targeting to Nucleus, Dicarboxylic Acid Transport
抗原
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