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ZAP70 抗体 (pTyr493)

This 兔 多克隆 anti-ZAP70 antibody specifically detects ZAP70 in WB, IHC 和 IF. The antibody is reactive with 人 samples.
产品编号 ABIN3020535
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for ZAP70 抗体 (pTyr493) (ABIN3020535)

抗原

See all ZAP70 抗体
ZAP70 (zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70))

适用

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克隆类型

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多克隆

标记

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This ZAP70 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
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    pTyr493

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Phosphorylated Antibodies

    免疫原

    A phospho specific peptide corresponding to residues surrounding Y493 of human ZAP70

    亚型

    IgG
  • 应用备注

    WB,1:2000 - 1:5000,IHC,1:50 - 1:100,IF,1:50 - 1:200

    限制

    仅限研究用
  • 缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    ZAP70 (zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70))

    别名

    ZAP70

    背景

    This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene.,ZAP70,ADMIO2,IMD48,SRK,STCD,STD,TZK,ZAP-70,Signal Transduction,Kinase,Tyrosine kinases,Cell Biology & Developmental Biology,Hippo Signaling Pathway,Immunology & Inflammation,T Cell Receptor Signaling Pathway,Protein phosphorylation,ZAP70

    分子量

    35 kDa/55 kDa/69 kDa

    基因ID

    7535

    UniProt

    P43403

    途径

    TCR Signaling, Ubiquitin Proteasome Pathway
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