Proteasome 26S S3 (Center) 抗体
This anti- antibody is a 兔 多克隆 antibody detecting in WB 和 IHC (p). Suitable for 人 和 小鼠.
Quick Overview for Proteasome 26S S3 (Center) 抗体 (ABIN2855348)
抗原
Proteasome 26S S3
适用
人, 小鼠
宿主
兔
克隆类型
多克隆
标记
非结合性
应用范围
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
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抗原表位
- Center
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交叉反应
- 大鼠
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交叉反应 （详细）
- Rat (93 %)
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产品特性
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Rabbit Polyclonal antibody to Proteasome 26S S3 (proteasome (prosome, macropain) 26S subunit, non-ATPase, 3)
Proteasome 26S S3 antibody [N1N3] -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human Proteasome 26S S3. The exact sequence is proprietary.
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亚型
- IgG
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anti-Proteasome 26S S3 (Center) antibody
适用: 人 WB, ICC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- Suggested dilution Reference IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceIHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*
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说明
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Positive Control: A549 , Hela , Jurkat , NT2D1 , NIH-3T3
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.23 mg/mL
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缓冲液
- 1XPBS, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Proteasome 26S S3
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背景
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The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the non-ATPase subunits of the 19S regulator lid.
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分子量
- 61 kDa
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基因ID
- 5709
抗原
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