TPSB2 抗体 (Middle Region)
Quick Overview for TPSB2 抗体 (Middle Region) (ABIN2774583)
抗原
See all TPSB2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- Middle Region
-
序列
- QALQRVGIVG GQEAPRSKWP WQVSLRVHGP YWMHFCGGSL IHPQWVLTAA
-
预测反应
- Human: 100%, Rat: 92%
-
产品特性
- This is a rabbit polyclonal antibody against TPSB2. It was validated on Western Blot.
-
纯化方法
- Affinity Purified
-
免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human TPSB2
-
-
anti-Tryptase beta 2 (TPSB2) (AA 30-276) antibody
TPSB2 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tryptase beta 2 (TPSB2) (AA 30-274) antibodyTPSB2 适用: 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tryptase beta 2 (TPSB2) (AA 31-275) antibodyTPSB2 适用: 人 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tryptase beta 2 (TPSB2) antibodyTPSB2 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Tryptase beta 2 (TPSB2) (AA 32-276) antibodyTPSB2 适用: 小鼠 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-Tryptase beta 2 (TPSB2) (AA 1-275) antibodyTPSB2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Tryptase beta 2 (TPSB2) (AA 35-275) antibodyTPSB2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeat freeze-thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
-
- TPSB2 (Tryptase beta 2 (TPSB2))
-
别名
- TPSB2
-
背景
-
Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. These genes are characterized by several distinct features. They have a highly conserved 3' UTR and contain tandem repeat sequences at the 5' flank and 3' UTR which are thought to play a role in regulation of the mRNA stability. These genes have an intron immediately upstream of the initiator Met codon, which separates the site of transcription initiation from protein coding sequence. This feature is characteristic of tryptases but is unusual in other genes. The alleles of this gene exhibit an unusual amount of sequence variation, such that the alleles were once thought to represent two separate genes, beta II and beta III. Beta tryptases appear to be the main isoenzymes expressed in mast cells, whereas in basophils, alpha-tryptases predominate. Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic and inflammatory disorders.
Alias Symbols: TPS2, tryptaseB, tryptaseC
Protein Size: 282 -
分子量
- 31 kDa
-
基因ID
- 64499
-
NCBI登录号
- NM_003294, NP_003285
-
UniProt
- P20231
抗原
-
