CAMLG 抗体
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- 抗原 See all CAMLG 抗体
- CAMLG (Calcium Modulating Ligand (CAMLG))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CAMLG antibody is un-conjugated
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应用范围
- Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF)
- 产品特性
- Homo sapiens calcium modulating ligand (CAMLG)
- 纯化方法
- Purified from mouse ascites fluids by affinity chromatography
- 免疫原
- Full length human recombinant protein of human CAMLG(NP_001736) produced in HEK293T cell.
- 克隆位点
- 2H3
- 亚型
- IgG1
- Top Product
- Discover our top product CAMLG Primary Antibody
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- 应用备注
- WB 1:2000, IF 1:100, FLOW 1:100,
- 说明
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The concentration of the product may vary between diferrent lots.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.5-1.0 mg/mL
- 缓冲液
- PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
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- 抗原
- CAMLG (Calcium Modulating Ligand (CAMLG))
- 别名
- CAMLG (CAMLG 产品)
- 背景
- The immunosuppressant drug cyclosporin A blocks a calcium-dependent signal from the T-cell receptor (TCR) that normally leads to T-cell activation. When bound to cyclophilin B, cyclosporin A binds and inactivates the key signaling intermediate calcineurin. The protein encoded by this gene functions similarly to cyclosporin A, binding to cyclophilin B and acting downstream of the TCR and upstream of calcineurin by causing an influx of calcium. This integral membrane protein appears to be a new participant in the calcium signal transduction pathway, implicating cyclophilin B in calcium signaling, even in the absence of cyclosporin.
- 分子量
- 32.8 kDa
- 基因ID
- 819
- NCBI登录号
- NM_001745
- HGNC
- 819
- 途径
- EGFR Signaling Pathway
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