CAMLG 抗体
Quick Overview for CAMLG 抗体 (ABIN2717006)
抗原
See all CAMLG 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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产品特性
- Homo sapiens calcium modulating ligand (CAMLG)
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纯化方法
- Purified from mouse ascites fluids by affinity chromatography
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免疫原
- Full length human recombinant protein of human CAMLG(NP_001736) produced in HEK293T cell.
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亚型
- IgG1
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应用备注
- WB 1:2000, IHC 1:150, IF 1:100, FLOW 1:100,
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说明
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The concentration of the product may vary between diferrent lots.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5-1.0 mg/mL
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缓冲液
- PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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- CAMLG (Calcium Modulating Ligand (CAMLG))
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别名
- CAMLG
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背景
- The immunosuppressant drug cyclosporin A blocks a calcium-dependent signal from the T-cell receptor (TCR) that normally leads to T-cell activation. When bound to cyclophilin B, cyclosporin A binds and inactivates the key signaling intermediate calcineurin. The protein encoded by this gene functions similarly to cyclosporin A, binding to cyclophilin B and acting downstream of the TCR and upstream of calcineurin by causing an influx of calcium. This integral membrane protein appears to be a new participant in the calcium signal transduction pathway, implicating cyclophilin B in calcium signaling, even in the absence of cyclosporin.
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分子量
- 32.8 kDa
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基因ID
- 819
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NCBI登录号
- NM_001745
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HGNC
- 819
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途径
- EGFR Signaling Pathway
抗原
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