Bcl-XS/L 抗体
Our Local Distributor
北京 101111
Quick Overview for Bcl-XS/L 抗体 (ABIN2666266)
抗原
适用
宿主
克隆类型
应用范围
克隆位点
-
-
纯化方法
- The antibody was purified by affinity chromatography.
-
亚型
- IgG2a kappa
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
浓度
- 0.5 mg/mL
-
缓冲液
- phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide at 0.5 mg/mL.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C
-
储存方法
- Upon receipt, store undiluted at between 2°C and 8°C.
-
-
- Bcl-XS/L
-
背景
- Bcl-X is one of the members of Bcl-2 family proteins, and exists in several isoforms generated by alternative splicing and plays a critical role in the control of apoptosis. The large isoform Bcl-XL (30KD)contains the highly conserved BH1 and BH2 amino acid domains and protects cells against apoptosis, whereas the short isoform, Bcl-XS(18KD) which deletes the conserved BH1/BH2 domain by alternative mRNA splicing, promotes apoptosisby interacting with Bcl-XL and Bcl-2.Bcl-X(S) is expressed at high levels in cells that undergo a high rate of turnover, such as developing lymphocytes. In contrast, Bcl-X(L) is found in tissues containing long-lived postmitotic cells, such as adult brain.Clone 2H12 has been shown to be useful for western blotting and immunoprecipitation, immunohistochemistry, and immunofluorescence of the Human, Mouse and Rat Bcl-XL and Bcl-XS proteins.
抗原
-