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CD8 alpha 抗体

This anti-CD8 alpha antibody is a 小鼠 单克隆 antibody detecting CD8 alpha in FACS. Suitable for 大鼠.
产品编号 ABIN2664859
发货至: 中国

Quick Overview for CD8 alpha 抗体 (ABIN2664859)

抗原

See all CD8 alpha (CD8A) 抗体
CD8 alpha (CD8A) (CD8a Molecule (CD8A))

适用

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大鼠

宿主

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小鼠

克隆类型

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单克隆

标记

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This CD8 alpha antibody is un-conjugated

应用范围

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Flow Cytometry (FACS)

克隆位点

OX-8
  • 纯化方法

    The antibody was purified by affinity chromatography.

    亚型

    IgG1 kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    The antibody solution should be stored undiluted between 2°C and 8°C.
  • 抗原

    CD8 alpha (CD8A) (CD8a Molecule (CD8A))

    别名

    CD8a

    背景

    CD8a is a 32 kD glycoprotein also known as T8, Lyt2, Ly-2, and CD8α. CD8a is a member of the immunoglobulin superfamily expressed on most thymocytes, subset of mature T cells, most NK cells, macrophages, and some activated CD4+ T cells (not resting). CD8a forms heterodimers with the CD8β chain (CD8b) on the surface of most thymocytes, while mature peripheral T lymphocytes express almost exclusively the CD8 αβ heterodimer. Intestinal intraepithelial lymphocytes express CD8a without CD8b. CD8 is an antigen co-receptor on T cells that interacts with MHC class I on antigen-presenting cells or epithelial cells. CD8 participates in T cell activation through its association with the T cell receptor complex and protein tyrosine kinase lck (p56lck).

    途径

    TCR Signaling
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